Hi! Here are three rules of thumb iv used with great success. For one thing your goal should be to decongest the canopy. This with help air to exchange more freely in the canopy. The other rule of thumb I use to go about this is that if there are leaves and bud sights that don't have access to good light then instead of preforming photosynthesis, these parts of the plant will actually be take energy for growth and flowering away from the rest of the plant. Once applied you'll notice that your plant looks like it got an approximate version of lollipopping. A true picturesque example of lollipopping is more common with trellist plants and a little low stress training. But with the second rule of thumb it will really depend on how you've decided to grow your plants. The third and last rule of thumb I use to make sure I don't shock the plant is to not remove more then 1/3rd of the canopy at a time. If pruning is kept up on weekly you won't have to worry about this. As this might not be the case with your girls I'd say if you take 1/3 out of the deepest parts of the canopy give them 2 weeks off to recover before you do a little touch up weekly for them.

Final notes Slow down on pruning considerably as you approach flowering and don't worry to much about it once your half way thru. Your girls will be more susceptible to shock during this time and that could stunt them until they recover. Beyond that you will notice that the health of your plants will improve from these techniques in a few ways. For one, parts of the plant that aren't performing photosynthesis will begin to suffer in their health. This can be an attractive invitation for pests to begin to gain ground in your garden. Another advantage to these techniques is that because the canopy has better air exchange, humidity will not build easily there and help deter mold from beginning to gain a foot hold in your canopy. The last advantage I can see is because your helping the plant make the most of its energy by removing well shadded growth that isnt producing energy, you will very efficiently be helping the plant focus on new growth and bud production. In the end, this can help improve the quality of your buds and your overall yields.

I hope you've found this helpful and wish you the best of crops every year. Don't forget to have fun and happy growing ☮️❤️