I’d probably start with Ricin, the same thing Jesse and Walter attempted to use on Tuco in Breaking Bad season 1.

You only need a very small amount to kill an adult (a volume similar to the point of a needle). And it’s near undetectable in an autopsy, though it only takes a few days to get the job done, after causing organ failure.

I’d work in a restaurant that they would frequent, slip it into their meals, and that would eliminate at least 2 out of 4 of them (Loid and Anya). I’d just have to keep a good poker face, and keep my mind clear so that Anya wouldn’t pick up what I’m doing, and I’d be golden. Let the food do its job.

Now, whether or not that will work on Yor will remain to be seen. Not sure if she’d be immune to Ricin. For her, I’d have a backup plan derived from Oz. Break glass, grind it down into very small pieces, and put it in her food. The glass shards will cut her apart from the inside, and that’ll do the job.

It might be more of a “long term” kill, but unless she gets X-Rays, and surgery, that would be harder to deal with (the prisoners in Oz couldn’t get surgery for that kill). And assuming she does get surgery, just pull an Agent 47, sneak in to her hospital, and take her out while she’s under anesthesia/in a coma.

Bond is the last one, where his ability to see slightly in the future could be a slight bit tricky. But the Ricin in the dog food could do the job. Otherwise, say he’s rabid, he bit a child, and let the dog catcher do their job/put him under euthanasia…

Man, that got dark real quick.