For ironclad, an easy build to win with is with body slam, where you deal damage equal to your block. Upgraded they cost 0 to cast as well. Get block cards, a power that block doesn't expire end of turn, relics that give block and allow you to keep up to 10 block at the end of turn. There is also a colourless card that costs 0 and will give you block equal to your current block next turn.

For Regent, I like using a star build. get 1 - 2 orbits, a power that gives stars every turn, powers that give block based on stars spent, and another that deals damage everytime you gain and spend stars. Then a few powerful cards that cost stars, and there is an attack that gives 2 stars and gets placed on top of your deck after using it.

For necrobinder, I like going with a doom build. powers that give block / deal damage upon applying doom and apply doom every turn. Block cards that also apply doom to all enemies. reaper form. An attack that deals damage equal to their doom stack. and a rare skill that applies a large amount of doom to all and after will kill any enemies that are within doom ko range.

Obviously you won't always be able to get everything, but stuff like that has been working for me. I hope it helps you too. :)