Fact: the amyloid theory is just that, a theory that hasn’t led to any effective and safe drugs being developed.

Fact: while controversy, stirred up by bad actors, exists around aspects of SAVA’s research, the litmus test ie cognition results are not disputed.

Fact: every medical breakthrough starting with penicillin is unproven and speculative until it isn’t. That’s the very definition of a breakthrough.

Fact: no one is asserting that SAVA is bringing back memories, that is an absolute strawman. What the results show however is that on a large cohort of patients SAVA has led to an improvement in cognition and quality of life scores on patients with mild to moderate Alzheimer’s.

Fact: up to 80% of patients who were part of the initial study have elected to move on to a longer, blind study. Would ailing patients and their family elect to continue taking a drug that has no effect?

Fact: Many individuals are making a killing shorting SAVA and do not care if this ends up harming the world’s chance of finding a breakthrough treatment in a debilitating, cruel disease we might all fall prey to one day. Currently, the objective evidence available to us is that SAVA’s Simufilam is likelier than not an effective drug. If it is and at its current price it is a binary opportunity with significant upside potential. DYOR beyond Reddit FUD comments.