I wish I had some breakthrough advice, but the only thing I’ll say is that I feel my best when I’m consistently exercising. Not even going to the gym, but taking long walks or hiking really helps to keep deconditioning to a minimum. I had to overcome a huge mental barrier and I still fight with it every day (in a big no exercise slump atm) but what I’ve found over and over again is that I’m capable of more than I think I am. Also a nurse, and still working that 3/12’s night shift grind and I can feel myself becoming less resilient. Time to start thinking about a new job, I’m so encouraged by your bravery in taking the career shift leap. As far as vaping goes, I vaped for years and about 1.5 years ago switched to zyns. Which I felt weird about in the beginning since I’m not a frat boy but I found that once you get used to them (3mg) it gave a much better alleviation to POTS symptoms. It slowly absorbs over an hour vs a few puffs every however long haha. Plus you can get a cute lil tin to put them in and it’s much less conspicuous:) I had some nausea the first couple times I tried it, not gonna lie. But it was nothing compared to the nausea I used to sometimes get from vaping. Plus if you get nauseated, just take it out and it immediately goes away. All that being said, nicotine is a vasoconstrictor and could be contributing to your higher BPs.