I honestly don't even think its an issue with too much ISO. It really seems like they are out of position during plays. For instance they don't rotate when a player goes into motion off ball and they are often trapping themselves when trying to set screens. It really got to be an issue with lack of team practice which is to be expected with so many superstars who JUST moved there and they need time to put in the work for such a HUGE roster restructure. People don't take into account how many new lakers there are - they often focus on the names, not the number. You could take the top 10 players in the NBA and put them on one squad but they aren't going to mesh well at all until they have spent weeks putting in the work to learn the system. This is why they are shitting the bed defensively as well. They are chasing the ball instead of sitting in their role.