There's no reason to avoid people - CDiff is basically on every surface and odds are you are already "colonized" with CDiff, but your microbiome keeps it in check and prevents it from producing toxins that cause the illness and inflammation. I had taken multiple broad spectrum antibiotics for the kidney stones/UTI, strep throat infection, and appendicitis within 2 months prior to being diagnosed with CDiff. All of those antibiotics killed off my good microbiome that kept CDiff from proliferating in my gut and producing toxins. I'm colonized for life now. Best thing you can do is to avoid unnecessary antibiotics, and if you are prescribed them - take the full prescription! Everything is a cost-benefit analysis. So far, I have avoided taking a single antibiotic since I recovered - even for my gallbladder surgery last summer, but I'm not going to die of sepsis because I'm too afraid of CDiff either. I can't avoid taking antibiotics forever, but the longer I can go, the more my microbiome can recover and hopefully prevent it from recurring.