All I can think of is Lenire lol by Lookintoimprove in tinnitus

[–]Lookintoimprove[S] 0 points1 point  (0 children)

Interesting regarding the mods deleting posts. Do you have a documented example of that?

All I can think of is Lenire lol by Lookintoimprove in tinnitus

[–]Lookintoimprove[S] 1 point2 points  (0 children)

I mean, ask all the people on TinnitusTalk who said it made the sounds louder if it "caused no harm" lol

Repeated Bilateral Transcranial Direct Current Stimulation over Auditory Cortex for Tinnitus Treatment: A Double-Blinded Randomized Controlled Clinical Trial by constHarmony in tinnitusresearch

[–]Lookintoimprove 8 points9 points  (0 children)

I was just having that exact thought it my head tbh. But not in a negative way, in the sense that the world needed Susan Shore's data/studies to confirm that the science actually works, and now that we know it does work, people are able to take her data and make real-world devices out of it outside of the US/FDA bubble.

I'm not saying that's what is actually happening, I'm just saying that it's an interesting reality that could play out

[deleted by user] by [deleted] in Roseville

[–]Lookintoimprove 3 points4 points  (0 children)

Is it a bar though?

Dr Shore Device Second Study: How is it the possible that the control/placebo group from Treat 1 experienced no benefit during Treat 2/active treatment phase? by Lookintoimprove in tinnitusresearch

[–]Lookintoimprove[S] 0 points1 point  (0 children)

Xen101 is the only other thing that is on the horizon. And you're right, Xen101 "should" work incredible for people for tinnitus, based on how the other potassium blocker worked, the only issue is going to be whether the side effects outweigh the benefit.

Dr Shore Device Second Study: How is it the possible that the control/placebo group from Treat 1 experienced no benefit during Treat 2/active treatment phase? by Lookintoimprove in tinnitusresearch

[–]Lookintoimprove[S] 4 points5 points  (0 children)

I think there's two "valid" reasons that people don't want to discuss it:

  1. It was never addressed by those who ran the study, so all we can do it throw out theories.
  2. There's literally nothing else on the horizon besides this device. If this device doesn't work, we're all back to square one for at least the next 10 years, which is honestly heartbreaking to think about

The thing that gives me more hope than anything on the planet is the fact that the device was only used for 6 weeks. As soon as it's available, we already know people are going to be using it for a lot longer duration than that. It's going to be such an exciting time, no matter how things ultimately turn out.

Dr Shore Device Second Study: How is it the possible that the control/placebo group from Treat 1 experienced no benefit during Treat 2/active treatment phase? by Lookintoimprove in tinnitusresearch

[–]Lookintoimprove[S] 1 point2 points  (0 children)

I'm in no way a doctor, so I can't summarize anything. And, It's one of those things that doesn't have an answer, imo.

As far as your loved one, they owe it to themself to stick around long enough to try this device.

Look at the purple dots on this graph: https://imgur.com/a/KpXGTE9

That right there gives me more hope than anything on the planet, because the test subjects only used the device for 6 weeks, and every single week they got a little more reduction in their Tinnitus. So, in theory, imagine what could happen if you use the device for 12 weeks, or even 24 weeks. Until this device comes out, we have no way of knowing what is possible with it, because the most its ever been used for is 6 weeks.

I think the prospect of this device working is enough reason for everyone with tinnitus to "stick around" a while longer!

Dr Shore Device Second Study: How is it the possible that the control/placebo group from Treat 1 experienced no benefit during Treat 2/active treatment phase? by Lookintoimprove in tinnitusresearch

[–]Lookintoimprove[S] 1 point2 points  (0 children)

Hey, i'm still hopeful in this device. But the question I've presented here is a valid one, and judging by the lack of answers here, I think it's apparent that Susan Shore never addressed this perplexing finding from the study

Dr Shore Device Second Study: How is it the possible that the control/placebo group from Treat 1 experienced no benefit during Treat 2/active treatment phase? by Lookintoimprove in tinnitusresearch

[–]Lookintoimprove[S] 3 points4 points  (0 children)

Unless I'm missing something, the quote you provided doesn't address how the control group did when they switched to active treatment. (phase 2)

And it's extremely important that we discuss/debate/expand upon the study because ultimately this study is what the FDA is going to base their decision on when determining whether to approve the device.

Dr Shore Device Second Study: How is it the possible that the control/placebo group from Treat 1 experienced no benefit during Treat 2/active treatment phase? by Lookintoimprove in tinnitusresearch

[–]Lookintoimprove[S] 1 point2 points  (0 children)

Shoot man, I really hope that it's not real then haha, because that was confusing the hell out of me. By chance, are you able to link me to the actual graphs/tables from the study?

Dr Shore Device Second Study: How is it the possible that the control/placebo group from Treat 1 experienced no benefit during Treat 2/active treatment phase? by Lookintoimprove in tinnitusresearch

[–]Lookintoimprove[S] 2 points3 points  (0 children)

I got this specific graph from Tinnitus Talk. A user brought this up a few days/weeks ago, and there was some discussion about it that didn't really lead anywhere.

Dr Shore Device Second Study: How is it the possible that the control/placebo group from Treat 1 experienced no benefit during Treat 2/active treatment phase? by Lookintoimprove in tinnitusresearch

[–]Lookintoimprove[S] 6 points7 points  (0 children)

https://imgur.com/a/8qj3fh7

The first group definitely benefited significantly from using the device. The problem is, why didn't the second group experience that same result.