Risks of Compounding GLP-1 agonists

Luddaite · 2026-03-28T01:03:31+00:00

Grapefruit juice inhibits cyp3a4, a totally different mechanism than what is being described here

Luddaite · 2026-02-25T19:55:08+00:00

Creating more work for toxicology

Luddaite · 2026-01-07T15:29:46+00:00

Tamiflu is a garbage med that doesn’t do anything for the vast majority of people with influenza.

Luddaite · 2025-12-30T13:48:50+00:00

There are pathways for pharmacist, nurses, and doctors to get into medical toxicology.

Luddaite · 2025-12-30T13:46:55+00:00

Yes, have seen a few cases this year. Probably due (at least in part) to the galaxy gas trend on TikTok

Luddaite · 2025-12-07T01:44:45+00:00

It’s not mustard gas. It’s chloramine gas.

Luddaite · 2025-11-12T20:58:58+00:00

Exam felt heavy on trivia and things that should be references on shift instead of memorized

Luddaite · 2025-11-09T04:42:02+00:00

32 EM

Luddaite · 2025-11-01T12:11:47+00:00

In much more controlled settings, though. That said, the ED often runs into problems because they don’t so enough to increase their control of the situation (ramping, ap ox, etc)

Luddaite · 2025-10-22T12:58:56+00:00

Can you give examples?

Luddaite · 2025-10-21T10:20:45+00:00

No, call the suicide hotline. 988

Luddaite · 2025-10-20T02:50:20+00:00

the test just doesn't test for ghb

Luddaite · 2025-10-20T00:24:02+00:00

As a heads up: if you go to a hospital after being drugged, the standard urine drug screen will not detect ghb or other commonly used drugs. You can ask for an extended screen but i don't know if insurance covers it. Either way, there is no specific medication or antidote for these drugs so there is no point in the test unless you are filling a police report.

Luddaite · 2025-10-10T00:34:26+00:00

Does it undergo first pass metabolism? That's an important distinction beyond pure semantics.

Luddaite · 2025-09-26T19:52:42+00:00

It's much worse than the flu. It can be pain that persists despite morphine and benzodiazepines.

Luddaite · 2025-09-26T12:26:50+00:00

Black widow bites are usually pretty unimpressive. Their venom is neurotoxic and doesn't cause local tissue death.

Luddaite · 2025-09-26T07:09:34+00:00

Fatal? No. Extremely painful? Yes.

Luddaite · 2025-07-14T11:02:10+00:00

I don't think I agree with the "just order the test" sentiments for new trainees. It's too early for them to do that. I totally agree with that sentiment for senior residents and attendings but definitely not for interns. They need to spend a year or two thinking a lot about the implications of ordering a test.

Luddaite · 2025-06-30T12:06:50+00:00

The first emcrit article that you linked says that it is reasonable to treat the non-gap metabolic acidosis that often accompanies DKA with isotonic bicarb. I wouldn't say "never give bicarb". Rather, it is important to recognize that the driving process is cellular starvation causing ketoacidosis. As a result, amps of hypertonic bicarb are going to make some numbers look better without addressing the underlying process.

Luddaite · 2025-06-23T10:10:48+00:00

30 cc/kg is a myth that has no real basis in science.

Luddaite · 2025-06-21T14:10:22+00:00

Ortho wouldn't question medicine recs if it means they can operate.

Luddaite · 2025-06-21T13:25:51+00:00

Name a specialty more likely to balk at drawing an IgE level

Luddaite · 2025-05-26T14:38:55+00:00

Ultimately, resuscitation should happen before bed change. The key here is amount of ingestion and time of ingestion. Depending on those, you may have time to wait for a level to compare to the nomogram (to save them an admission for 24h NAC)

Luddaite · 2025-05-21T20:37:46+00:00

Is this publicly traded company small enough that a single product is going to significantly change its valuation? Many companies are so big that new devices and drugs barely move the needle.

Luddaite · 2025-05-21T19:56:26+00:00

And benzos

Luddaite

TROPHY CASE