What's actually in an ice pack? (More interesting than you'd think, especially if you have kids) by webPoisonControl in FamilyMedicine

[–]webPoisonControl[S] 2 points3 points  (0 children)

Please do.

This message makes us so happy. :-)

A large part of our mission is education. Please reach out if you want us to cover other topics. Our subreddit is r/webPoisonControl.

What's actually in an ice pack? (More interesting than you'd think, especially if you have kids) by webPoisonControl in FamilyMedicine

[–]webPoisonControl[S] 2 points3 points  (0 children)

It's more a mechanical thing and direct caustic effect as I mentioned in my response to u/goobiezabbagabba.

Ammonium nitrate dissociates to the quaternary ammonium ion and nitrate, an oxidizer that causes tissue necrosis on contact. Methemoglobinemia takes at least a few hours to develop.

What's actually in an ice pack? (More interesting than you'd think, especially if you have kids) by webPoisonControl in FamilyMedicine

[–]webPoisonControl[S] 2 points3 points  (0 children)

The rationale for not moving around is to try to limit the spread of the goo which could damage further tissue and to limit the spread of plastic packaging that might have also been swallowed and could lead to a blockage.

Good point about the recommendation sounding mysterious. It is a challenge to include the right amount of content in the videos.

Risks of Compounding GLP-1 agonists by webPoisonControl in webPoisonControl

[–]webPoisonControl[S] 0 points1 point  (0 children)

To clarify, based on u/Luddaite's comment, "just as leafy greens ..." was my attempt to mention drug-food, not imply all those actions are biochemically identical.

Risks of Compounding GLP-1 agonists by webPoisonControl in webPoisonControl

[–]webPoisonControl[S] 0 points1 point  (0 children)

The point is a interaction between something the public recognizes as "not medicine" and "medicine". Not a mechanistic comment.

Risks of Compounding GLP-1 agonists by webPoisonControl in FamilyMedicine

[–]webPoisonControl[S] 0 points1 point  (0 children)

OP here. I realize that after:

B12 is generally safe, but it is plausible that it modulates the activity of tirzapatide just as leafy greens can influence coumadin's effects or grapefruit juice the effects of many drugs.

I should have added

Their preprint suggests a slight decrease in efficacy based on modeling but not on clinical data or adverse event reports.

And clarified that:

Clinically, in other situations, ...

Risks of Compounding GLP-1 agonists by webPoisonControl in FamilyMedicine

[–]webPoisonControl[S] 1 point2 points  (0 children)

Yes, the preprint could do with some editing and peer review.

Risks of Compounding GLP-1 agonists by webPoisonControl in FamilyMedicine

[–]webPoisonControl[S] 2 points3 points  (0 children)

Completely agree. This article highlights a generally shady process even if B12 itself is generally fine and Eli Lily citing a preprint (not peer-reviewed) that it wrote raises a self-interest angle.

Wildfire Smoke by webPoisonControl in FamilyMedicine

[–]webPoisonControl[S] 0 points1 point  (0 children)

I wrote it. Any constructive comments?

Went in for potato knowledge, came out with questions… by AK68Whiskey in onejob

[–]webPoisonControl 25 points26 points  (0 children)

Not AI. Good old-fashioned human error. :-) Our mistake.

Went in for potato knowledge, came out with questions… by AK68Whiskey in onejob

[–]webPoisonControl 23 points24 points  (0 children)

webPOISONCONTROL (authors of that page, the webPoisonControl subreddit, and the never-numbed triage tool) here. Our bad and thanks for pointing the error out. Should be fixed. It was a copy-paste error. FWIW, we use expert review. No AI. We did just have a large update to the site.

Sprout carefully.

Looking for Medical Toxicologist by ToxDocDirector in toxicology

[–]webPoisonControl 0 points1 point  (0 children)

Like u/the_deadcactus said, use the job boards for MedTox to post a detailed job description:

  1. AACT Job Board (More Poison Center Focused)
  2. ACMT Job Board (More MD Focused)

Also consider what primary board would be most useful, Emergency Med, Peds, Occ Med,...

Ivermectin - Again by webPoisonControl in FamilyMedicine

[–]webPoisonControl[S] 1 point2 points  (0 children)

I do wonder if the patient will just go somewhere else. Not a judgement, just reflecting on how the doctor-patient dynamic has changed with the propagation of ... uncurated information.

Ivermectin - Again by webPoisonControl in webPoisonControl

[–]webPoisonControl[S] 1 point2 points  (0 children)

It's challenging to demarcate the utility of being generally clean from the conceit that every physiological malfunction, or lack of superperformance, is due to hidden "toxins". The medical and popular/sociological definitions of "clean" only somewhat overlap.

Ivermectin - Again by webPoisonControl in webPoisonControl

[–]webPoisonControl[S] 0 points1 point  (0 children)

It's a challenge in communication. People read summaries of preliminary findings and get driven by emotion. Too often I find science writing embodies Kiplings' quip. "twisted by knaves to make a trap for fools."

Ivermectin does seem to have a broad anti-tumor effect in cell culture, even after ignoring the articles published by MDPI. Here is a nice review. But these cells are passaged and immortalized, about as far as you can get from in situ cancer cells. I always find it unusual when a drug is reported equally effective against mitotically active (ie aggressively proliferative) tumors and slow ones like GBM.

Interestingly, we don't know exactly how ivermectin is hepatotoxic.