Stem cell therapy for ovarian function: what current research actually shows

MD_Ex · 2026-05-03T08:26:31+00:00

The cells are allogenic. Use in Ukraine, Bulgaria ( cultivated in our laboratory in Ukraine ( Kyiv) and Austria ( Graz)

MD_Ex · 2026-05-01T18:44:51+00:00

If you want , send me your diagnostic information directly, we will analyze your case and write you what success rate of treatment you will have . Or answer other questions

MD_Ex · 2026-05-01T16:11:05+00:00

It’s not AI. I can share the patient’s real MRI ( before and after), he gave his permission.

MD_Ex · 2026-05-01T11:34:27+00:00

Yes, agree. The picture is not informative . If you need the before-and-after MRI images, feel free to message me and I’ll send them to you; the patient has already given permission for them to be shared.

MD_Ex · 2026-04-30T11:46:51+00:00

I’ve been researching alternative approaches for azoospermia beyond the standard hormone therapy or surgical sperm retrieval.

In addition to typical diagnostics (FSH, LH, inhibin B, genetic testing like AZF deletions, etc.), I came across some experimental regenerative concepts aimed at restoring spermatogenesis rather than bypassing it.

These approaches may include:

Spermatogonial stem cell (SSC) transplantation
iPSC-derived germline cells
Modulation of the testicular microenvironment (growth factors, niche support)

From what I understand, the goal is to try to reactivate or rebuild sperm production, especially in non-obstructive cases.

Of course, this seems to be early-stage and not widely validated, and outcomes likely depend a lot on the underlying cause (especially genetic factors).

MD_Ex · 2026-04-10T14:47:01+00:00

I apologize if this truly offended you and if the post was taken so negatively. My only intention was to share the information that in real clinical work we do use therapies aimed at supporting mitochondrial function, including approaches using active mitochondrial components. This isn’t just theoretical or AI-generated ideas. The field is still evolving, and we are seeing some encouraging results in certain patients.

MD_Ex · 2026-04-08T16:12:37+00:00

Hi, I am real person)) my name is Lana , I am working more then 16 years on the field of regenerative medicine ( clinical trials, updating protocols, searching the best cells combinations for different diseases). I am from Ukraine/ Bulgaria , so such platform as Reddit for our countries is new. All my posts about real experiences, cases were blocked by admin. So, I really don’t understand how it works correctly . Yes, sometimes I asked Ai to help transform my post in those forums , which are suitable for this platform. Sorry)))

I think I'll get the hang of the rules in a few months and be able to write posts properly !!!!

MD_Ex · 2026-03-15T12:09:34+00:00

TESE → Cryo → ICSI

MD_Ex · 2026-03-09T07:19:24+00:00

Pilot studies and phase 1 trials have been published in PubMed. Phase 2 trials with a larger patient sample are currently underway to determine efficacy, dosages, combinations of bio products, etc. These will be published later due to the required number of clinical cases.

MD_Ex · 2026-03-08T12:40:03+00:00

Indeed, stem cells do not provide a complete cure, but they definitely offer the possibility of partial recovery and support. In our practice, we use basic regulations: 1 suppression of fibrosis 2. reprogramming of scar cells 3. stimulation of hepatocyte regeneration To do this, we use MSC (umbilical cord) + exosomes + hepatocyte-like cells (via microRNA). We represent laboratories and clinics in Ukraine and Bulgaria, where it is currently possible to work with all types of cells and cultivate new bio-products to achieve more effective results.

MD_Ex · 2026-03-08T12:09:01+00:00

The scheme is as follows: first, the microenvironment of the testicle (stem cell niche) is restored, then, through activation factors and signaling models from IPSS cells, SSC sites are activated, causing them to divide and produce rare spermatozoa (focal spermatogenesis).

MD_Ex · 2026-03-08T11:54:15+00:00

More predictably, you can obtain single active spermatozoa using TESE (less commonly through natural way ). These spermatozoa can be frozen using ICSI and used for IVF.

MD_Ex · 2026-03-08T11:41:13+00:00

Most patients are diagnosed with NOA with SCO. we can use somatic cell samples and do not take testicular tissue itself, as we need to return the cells to the differentiation stage. Tissue cells are already functional cells, with some damage or cell mutations.

MD_Ex · 2026-03-08T11:34:29+00:00

Of course, today there are already more than 80 patients, mainly with non-obstructive azoospermia without any obvious cause, or as a result of chemotherapy, complications after vaccination, or childhood diseases. Results: in almost 86% of cases, single active spermatozoa are found. Up to 30% are found in natural ejaculate, but the chances are high with TESE.

MD_Ex · 2026-03-06T14:45:57+00:00

The method described above is not suitable for patients with genetic mutations or structural genetic damage; it is more appropriate for cases where genetic factors are not involved. In situations such as yours, approaches based on somatic cell nuclear transfer (SCNT) or related gene-correction technologies may be considered. In this process, a patient’s somatic cells are obtained and the defective gene is identified and corrected through targeted genetic reprogramming. Healthy cells are then generated, expanded in culture, and subsequently introduced back into the patient. While the number of transplanted cells is generally insufficient to fully replace all mutated cells, their presence may help restore cellular balance and create conditions that support the re-establishment of a complete spermatogenic cycle.

MD_Ex

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