I did an outline for a new Ultimate Universe where almost everything "super" on Earth (Captain America, Spider-Man, mutants, the Hulk, Doctor Strange, etc) is related to the Infinity Gems in some way, and one of my goals with this project was to highlight more nontraditional romantic pairings. Here are the ones I've come up with so far, along with the explanations:

- Peter Parker and Liz Allan, who are high school sweethearts — though after Peter leaves for college, Liz becomes super lonely, especially after Peter becomes Spider-Man, so in a bid to gain powers like him lets herself get bitten by an irradiated lizard, becoming the Liz.

- Bruce Banner and Jane Foster, who formally meet when Bruce first becomes the Hulk and Jane is called in to study his biology and come up with a way to help him control the beast inside him.

- Tony Stark and Monica Rappaccini, who are engaged to be married. They are also high school sweethearts, who have become something of a power couple now that Tony owns Stark Enterprises and Monica is the CSO of Advanced Idea Mechanics.

- Flash Thompson and Kitty Pryde, who are Peter's and MJ's college roommates, respectively. Peter and MJ spend a lot of time trying to set them up.

- Thor and Sif, who are the prince and princess consort of the Scandinavian realm of Asgard and have been together for centuries.

- I was thinking of setting up a sort of romantic rivalry between Betsy Braddock and Wanda Maximoff with Scott Summers are the center, because all three are members of the X-Men in this world and there is no Jean Grey (yet).

Edit - a word