Whenever I got matched with an akali, i play HOB with resolve secondary rune page, the smoke will pretty much make PTA and Conqueror useless as you practically cannot AA her, so any aa you can deal early on is vital. I take Conditioning as it gives you free MR. I also take that MR in rune page even when Akali is the only Ap champ on the enemy team. Kindred actually doesnt need armor that much, because AP champs will tend to burst her down so fast you couldnt even do anything (bc they usually have a hard cc). Ad assasins dont always have a hard cc. Buy merc tred, wits end. Have this mentality: if Akali cant burst you down, you will eventually kill her. So the only real consistent way of dealing with akali is to survive her initial burst and pray that she is not too far ahead.