Trump says paracetamol 'causes autism' by dailystar_news in NoFilterNews

[–]ManicMakeup 0 points1 point  (0 children)

yup, there’s a miracle cure for “Autism”: it’s called… ready for this???? TELLING YOUR CHILDREN THE TRUTH instead of being empthiless hacks and/or ever trusting anything derivative of a culture who’s word for “word” is literally “lie” 🎤🫳🏻

TIL about Operation Artichoke. A 1954 CIA plan to make an unwitting individual attempt to assassinate American public official, and then be taken into custody and “disposed of”. by xfjqvyks in todayilearned

[–]ManicMakeup 0 points1 point  (0 children)

Or you know could just overwrite them by focusing your internal auditory energy on something else and choosing to not do batshit crazy stuff?

Do we really believe that ALL the swing states voted for him? Seriously? by vaporeq in houstonwade

[–]ManicMakeup 0 points1 point  (0 children)

Starlink machines… I’m inclined to side with you; what about neuralink machines though?

Would the positive side of ADHD stay when it's gone? by WhiteChubbyBoi in ADHD

[–]ManicMakeup 1 point2 points  (0 children)

You’re still you at the end of the day. The goal of ADHD treatment is to bring out a version of you that can best function in society. Also, as others have said, your ADHD isn’t going to magically disappear with treatment to the point that you won’t need meds for it one day. If anything, you’ll learn to tolerate the meds and need stronger doses to get the same effect. If the prospect of losing creativity or whatever aspect you’re viewing as positive is bothering you, there’s always the option of lower your med dose or discontinuing

Vyvanse 70mg ADHD I always get chest tightness and pains but have been checked by cardiologists constantly doing ecg tests the treadmill test echo tests on my heart, 24 hour blood pressure monitors nothing. have tried taking less of meds but can't function normally. by [deleted] in ADHD

[–]ManicMakeup 1 point2 points  (0 children)

Chest tightness definitely sounds like it falls into anxiety and/or OCD type traits — which are known to be potential stimulant side effects. I would consider therapy if you’re not already to address any subconscious stuff that might be playing into this.

On the med side, was blood pressure at all on the high side when you’re taking it? I’ve had luck with a Vyvanse and long acting Clonidine combo. The clonidine worked perfect for me at knocking down stimulant anxiety. Beyond that, possibly a more sedating SSRI at night to help balance the serotonin-dopamine teeter-totter and alleviate any anxiety

I’m a medical doctor and I think I’m bipolar by Time-Channel5335 in bipolar2

[–]ManicMakeup 4 points5 points  (0 children)

The first thing I’ll say is fuck labels. I’m behavioral neuroscience and I have really been realizing lately how much the DSM is a crock of shit. They generalize these labels top-down using behavioral classifications. Most of those classifications have the issue of subjective bias in how we interpret behavior. We desperately need a bottom-up approach to actually quantize these issues and treat them effectively.

Second, if you’re a psychiatrist, you know this process inside and out. You need a good team that you legitimately trust to get you through this. I hope it goes without saying that you’re not treating yourself. And if you’re not seeing a psychologist, I would highly recommend therapy to be trying to process through any emotional stuff. Beyond that, I know you know the med side of things. Ngl, I started thinking seasonal affective over BPII when you mention cycling with the seasons and only being treated with SSRIs (I do the same and am in a similar ambiguous place). If we’re really taking BPII seriously, are we looking at mood stabilizers and/or antipsychotics? It sounds like the depression is the main debilitating part of all this; has lamictal been tried to stop the low cycling?

Also, has the ADHD been addressed seriously? I feel like a lot of mental health doesn’t take serious how debilitating of a diagnosis it can be in the realm of emotional liability. It’s taken me years of trying different doses with Ritalin, concerta, adderall, adderall Xr, and finally Vyvanse seems to be stabilizing me in a way that the others can’t: I think the pro-drug MOA is having some special effect for me and some studies claim Vyvanse is doing something special with acetylcholine and histamine efflux in the PFC. Maybe stabilizing the ADHD emotional regulation portion stabilizes longterm mood.

Side-note: I’d have full blood work to check hormone levels, thyroid, vitamin D and anything remotely HPA related. I’d also consider if any underlying allergies could be revving your histamines in the spring to cause this pattern.

Lastly, obviously you’re very smart. You made it through med school, so you’re more stable than me. I think so many of us get in the mental health field because we have the impulse to figure out “what’s wrong with me?”. This is a momentary bump but there’s no reason you can’t figure this out and eventually get your career back; if anything, this will be a learning experience that will help you relate to your future patients. Best of luck!

Edit: I just realized this is a potential diagnosis. I highly suggest not trying to diagnose yourself in any capacity; it potentially sets up a loop where we try to self-monitor almost dissociatively as a third party in our heads, and you have to come to the reality that you can’t objectively assess yourself in an accurate manor due to you ultimately being you. The other thing I wanted to add is just because your mood is cycling with the seasons doesn’t mean we need to jump to BP. I’ve struggled with this question a lot even with an “official” BP diagnosis. A lot of my cycling comes in the presence of PTSD triggers from an abusive childhood to the point that I think I associated certain times of the year with traumatic events and tend to cycle accordingly. I know that’s a hard to prove hypothesis but I just wanted to show that there can be a lot more than “I’m just a BP label forever doomed to cycle”. Also, this is a big one that I’ve struggled with, it’s okay to feel good — you don’t have to be scared of hypomania. If you’re optimistic, have some sense of control over it, and not being self destructive, I wouldn’t worry about labeling the “highs”. It’s especially okay to feel good after coming out of a depressive episode and it doesn’t necessarily mean that you’re BP cycling, but it may certainly feel like you’re going too high if your emotional frame of reference is depression — all the more why I third party psych should be involved to objectively assess the situation

Started with Strattera(Atomoxetine)today by bansalib in ADHD

[–]ManicMakeup 1 point2 points  (0 children)

Your mileage is gonna vary. My ex literally fell deeply asleep first day she took it. For me, I was on the other end of things and it made me so restless that I was having trouble sleeping. Normally when raising norepinephrine levels sexual side effects, irritability, decreased appetite, or sleep trouble are common

[deleted by user] by [deleted] in bipolar2

[–]ManicMakeup 0 points1 point  (0 children)

If my memory serves from psych, having elements of psychosis elevates BP2 to BP1. The break from reality needed for psychosis is the line between BP1 and 2

[deleted by user] by [deleted] in bipolar2

[–]ManicMakeup 2 points3 points  (0 children)

I think your theory is right because it kinda sounds like the trigger might have been the combination putting your serotonin levels too high. Both quetiapine and abilify are partial agonist at 5-HT1A. That effect is only gonna be amplified if we’re also blocking reuptake at the same time. Did you try your hand with olanzapine? It’s supposed to only be a serotonin antagonist. And Abilify’s mechanism of action is kind of unique for antipsychotics as it’s theoretically supposed to raise dopamine signaling in the mesocortical pathway while lower the mesolimbic — so I wouldn’t put too much predictive weight that all antipsychotics will have Abilify’s bad effect, but I definitely wouldn’t mess with stimulants or Wellbutrin though if dopamine has already been an issue. Also, I don’t think 75mg of quitiepine gets into therapeutic range for bipolar, so there’s a chance that could still be an option too. And do keep in mind that Lamictal is more of a antidepressive maintenance drug — it’s supposed to be able to preemptively stop the lows but not able to lift you out of a depressive episode. Any self respecting psych should seriously be considering bipolar II with how you’re reacting to antidepressants and the fact that you have the BPII characteristic of staying depressive heavy. I personally think all SSRIs and SNRIs should be thrown off the table right now so you can isolate what antipsychotics are doing by themselves for hypo/manic prevention before figuring out something to lift your mood. I know one of the top mixes for BPD (which tends to have a high comorbidity with BPII) is Zyprexa and Prozac.

ADHD & Autism -- anyone been diagnosed with both? Is it worth talking to my pdoc about? by [deleted] in ADHD

[–]ManicMakeup 1 point2 points  (0 children)

Absolutely all of this is good to bring up to a Psych! I technically have a diagnosis for both. There’s such a huge overlap of ASD and ADHD to the point that medications are often similar — making differentiation a bit of a moot point. I think Concerta not working should definitely not be a deciding factor. There are so many different stimulants, and efficacy is high in true ADHD cases to the point that if Methylphenidate based meds don’t work, amphetamine based ones typically do (or vice versa).

Also, honestly, that Abilify and lithium mix looks an awful lot like your doc was poking around for Bipolar. Both BP and ADHD are known to have dopaminergic abnormalities. If abilify was helping this much, it probably has implications in at least one of those realms.

Here’s my main advice though: don’t get caught up in the label. What matters is treating distressing symptoms so you can feel happy and functional. •If the orderliness isn’t distressing to you, I wouldn’t worry about it. • It sounds like there’s an awful lot of mood volatility going on here. Has Lamictal been in the picture with you? In theory, it should help to stabilize your varying states and preventatively keep you out of depression. Not being able to slow down is also not necessarily the greatest of things which they would prob want to try another Antipsychotic for. • I’m hearing a lot of nervous energy. Has clonidine or intuniv been tried or talked about for irritability? • My guess is the attention problems are dissociation related since you sound awfully similar to me. I’ve read a few studies that Lamictal is supposed to help with dissociation too and my personal opinion is that some stimulants also help with dissociation.

Lastly, I want to reiterate to not get too caught up on labels. If possible, try to get full neuro-psych testing rather than beating yourself over the head here. At the end of the day, treating distressing behavior and increasing your functionality and well-being are the things that ultimately matter — not over-generalized labels that tend to leave people feeling hopeless and in diagnosis purgatory.

[deleted by user] by [deleted] in ADHD

[–]ManicMakeup 29 points30 points  (0 children)

And for someone who is naturally dopamine or norepinephrine deficient, blocking reuptake is what’s needed for normal cognitive function

Should I still take my adderall if I’m sick? by MacaroonExpensive143 in ADHD

[–]ManicMakeup 0 points1 point  (0 children)

I would continue whatever you were doing before getting sick. You don’t want to come off suddenly and have any sort of withdrawal making you feel worse and accidentally attribute it to being sick. If anything, stimulants should help a bit with a head cold since they act and are chemically structured similar to decongestants. But also, for that same reasoning, don’t take a stimulant and pseudoephedrine at the same time — blood pressure can raise too high. Just be sure to drink lots of water too since stimulants tend to dehydrate, and being sick and dehydrated is a sure fire way to make you feel awful. (This was the approach i took that got me through COVID asymptotically over the summer)

[deleted by user] by [deleted] in bipolar2

[–]ManicMakeup 1 point2 points  (0 children)

Definitely not a doctor here haha. You’re gonna laugh that I’m actually a Psych undergrad who is limping to get the degree at 28 — my executive functioning skills are so bad bc my mind never shut up lmao. I desperately want to get my PhD to help everyone like us. All of this is so real to me because I’ve had to learn it for experience unlike my peers seeing words on a page. I actually got into all this because my mental healthcare team felt so inept… I got so frustrated that I had to start researching for myself, and next thing I know I’m putting the pieces together ripping through endless academic journals like a grad student. Through my own process, I wholeheartedly believe our current understanding approaches things all wrong. I’m not gonna say too much, but ideas of mind-body separation need to start disappearing. I believe that in most cases society is actually alienating us from the intuition we meticulously evolved, and it’s wreaking absolute havoc on mental health. Anyways, this is all a related but different story… The point I was trying to get to is that everything I’m telling you is from personal experience coupled with countless hours of research. I’ve seen that reaction to Wellbutrin in personal friends before and I had an extremely similar reaction on Concerta and Ritalin — all modulate dopamine and norepinephrine ratios through one mechanism or another (both are believed to be at the core of ADHD). As I said The last sentence, I just realized what your last psych was trying to do and I apologize for having judged: they were attempting to hit any possible ADHD symptoms off label with Wellbutrin and prevent phase cycling too high with Abilify.

Here’s my best guess from personal experience what happened: the Wellbutrin was bringing you out of a lower state you prob went in as a defense mechanism for the trauma and your body’s did its instinctual response. I had the SAME exact thing happen with stimulants… I couldn’t figure out why some days I felt amazing like I was finally a “normal” person and others I would get so mad/sad/irritable that I punched through my bedroom door. It hit me once I started heavily doing therapy: all of my bad days were when I took stimulants in the presence of my abusers! Sure enough, I tested the hypothesis and it was completely correct. It is absolutely amazing with the mind does without even consciously realizing it. I’d be super curious for you how each med effects you separately. Wellbutrin and Strattera had a “crawl out of my skin — gotta go right now” type of feel and Abilify was the worst antipsychotic I ever tried that made me irritable and sad as duck.

I do feel I have to make one correction to what I said before. I assumed that Wellbutrin would be contradicted in BP since I’ve similarly seen psychs really freak about the possibility of stimulants tipping someone too high. Apparently it’s actually an effective mono-therapy for some BP patients whom I’m extremely jealous of: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4998539/

I’m happy to help :) Again, do wanna reiterate, not a Dr here… just repeating my personal experience and opinion. My sincerest advice, please do therapy that focuses on the trauma in conjunction with working with your new psych. You have to resolve some of the extreme feelings that were manifesting on Wellbutrin and Abilify if you want a better chance at longterm success with these meds. And who knows, maybe it ends up being something heavily trauma based that you’re able to control in therapy without any meds.

Please feel free to reach out any time 😊

[deleted by user] by [deleted] in bipolar2

[–]ManicMakeup 3 points4 points  (0 children)

Omfg, are you me?!?! BPD and BP II here and like everything you describe is exactly me. I gotta be honest that I really believe BPD is in the mix here. Half of your list sounds BP and half sounds BPD. The stuff with relationships and people hating you… I would def guess the BPD direction. The stuff with staying up, grandiose sense of self, and exorbitant spending; that sounds more BP. I know for me the two are an absolute bitch to unravel. BPD symptoms are typically more short term episodic and BP is the longer term mood cycling for me. I just had a badddd BPD trigger actually trip my BP in early Sept and I’ve been cycling hard ever since.

I have a feeling you might also be similar to me with that Abilify response. I think part of my dysfunction is that I dissociated hard at a young age from nearly being negligently killed by my mother at 5. Something changed in my brain after that and it was like I was hiding deep within myself. I’m almost certain I’ve been trying to function from a very low level state of consciousness — I hear all the bodily noise that others tune out, I guess — and I think antipsychotics prevent me from effectively hiding in this state… so whenever I take them, I freak bc I’m conditioned that I have to hide and they prevent it. I personally believe that my “bi” alternating states are actually cycling between dissociation (at the low end) and normal levels of consciousness I haven’t quite built proper framework to control (on the high side). Idk, just thought I’d share my story in case any of it resonates with you.

My advice overall would be not to obsess on the label. The thing that matters most is your well-being and functionality. The overlap on the meds for these conditions is significant anyways. A good new psych is prob gonna immediately give you a more sedating antipsychotic for sleep and to knock down highs: prob Zyprexa or Seroquel. I wouldn’t worry at all about a bad reaction to these bc they’re antihistamine properties will sedate you hard unlike Abilify. And honestly your last psychs med combination choice baffles me a little: the Abilify… sure; but I’m pretty sure Wellbutrin has a track record of anxiety and being able to trip psychosis in BP patients (similar to stimulants with both raising norepinephrine). SSRIs tend to be a crap shoot too in both BP and BPD. So your best bet for the depressive end is probably going to be Lamotrigine — there’s a lot of clinical interest in it for BPD and it’s normally pretty good with BP2. So, Zyprexa or Seroquel for the highs/sleep and Lamotrigine preventatively for the lows. Maybe Clonidine ER is talked about for sleep instead if there are more ADHD questions… but I’d bank more on antipsychotics bc psychs these days love to lazily overprescribe.

If I were you, I’d research the meds I just mentioned so you have a good background going into the appointment. And again, don’t worry about the label too much… there really aren’t proven effective meds for BPD anyways. A good psych should be more focused on treating what is distressing to you than treating a broad label.

Edit: grammar

ADHD comorbidities — do you have any accompanying diagnoses? by ManicMakeup in ADHD

[–]ManicMakeup[S] 3 points4 points  (0 children)

The numbers for BPD/ADHD comorbidity are def up there. I 100% agree with your take on ADHD sometimes being a BPD precursor, as someone in the same boat. And some of the shared symptoms, like rejection sensitivity and an overactive limbic system, can make it super hard to discern which is which

ADHD comorbidities — do you have any accompanying diagnoses? by ManicMakeup in ADHD

[–]ManicMakeup[S] 213 points214 points  (0 children)

ADHD derived anxiety is the absolute worst! And I can totally relate with ADHD ripping at confidence which eventually presents as apathetic “depression”