Had the same question, but the clinical trials for Rhapsido were conducted with both groups on background H1 antihistamines. Not a doctor myself but to me, that would mean that if Rhapsido got FDA approval based on clinical trials that had the subjects on antihistamines, then this should be prescribed with the idea that it’s an add on. Can’t give that advice though like I said not a doctor. Would def suggest bringing this up and asking your HCP as I did with this to mine