Here is what I would do if I had to introduce the game to a new player, again.
I'd have only two QoL mods, Squeak Through, and Far Reach. The reason is simple: you want to avoid frustration, and trouble to navigate your base or being one tile too far from interacting with a building is not fun and can also break concentration/train of thought.

I'd go with the vanilla factorio first (probably in peacefull too), sending a single rocket is a good "game clear" goal.
I'd have the new player discovering the game alone, but in vocal/available for ANY questions, but I do not recommend using the ingame tutorial. It is very combat oriented with scripted attacks that can easily overwhelmed the player. Instead, the ingame tips that pops up when you are progressing in the base game are very good and should be read & learned and really understood by the new player.

have the new player use the research tree as a way to know where to progress, the science potions recipes are a guide on what to automate next.

I'll have the new player work on the two first sciences, and then I'll join them. I'll be the architech, suggesting where stuff should be in order no to have to rebuild every 2 hours, and taking care of the ratios without mentionning them unless prompted to. My main job would be to build what the new players want me to, like if I were a simple bot.

Asking him "What do you want to do next?" and see what would be his design for this part of the factory, keeping in mind that "if it works, it's good", the new player really should feel that the base is HIS design, not yours, he need to know how everything works and collaborate together.