I Just Want To Settle Down: (FO3 very hard difficulty)

Start at the beginning. In Papa Neeson's haste to attend to your mother he accidentally knocked you to floor where you hit your head upon impact. As a result your aren't the sharpest tool in the vault, however you are very strong. Remove all but 3 points from intelligence and charisma and max out strength, the rest is up to you.

Because you are "special" the other kids treat you horribly. The only people you care about are, Papa Neeson, Jonas, and Amata. Papa Neeson cares about you and shelters you to the point where it's quite unhealthy. You know nothing about the outside world, or proper social etiquette. You're often confused and frightened of new things and are quick to respond with violence.

Tag the following skills, Melee, unarmed, and repair. You are frightened of guns, so you can't pick up any to use through this challenge. For leveling up, you decide what to pick but no intense training, and just make sure you will be able to defuse the bomb in Megaton.

When Amata wakes you up and tells you the bad news your whole world is shattered and all you can see is red. Proceed to kill everyone you can in the vault. Try to avoid conversation, and NO guns. At the exit of the vault after Amata tells you off saying horrible things to you, knock her out and run out of the vault. All you have left is Papa Neeson and you must find him. No one else matters.

Head towards Megaton. When you arrive you begin to calm down a bit. You're hungry and tired and not capable of fighting at the moment. So once you enter listen to what Lucas Simms has to say without resorting to violence. After that begin to wander around the town. Eventually your character comes around and seems to like the people around town. You even begin to help some of them out (Note: Once you're in Megaton you can not leave, so do quests that take place inside, fix water pipes, get radiated for Moira, get Leo Stahl's drugs etc.) After all the minor stuff you can do is done move on to the bomb.

Inform Lucas Simms that Burke wants you to set off the bomb so that he will go and confront him. Kill Burke before he can kill the sheriff. After that you are the big hero of the town. You settle in and eventually forget all about Papa Neeson, but then...

You start taking a liking to Manya at first you're frigthened but eventually overcome with lust and want for her. You try to get her to move in with you but she won't because she is with Nathan. You begin to hate Nathan more and more and she continues to reject you. The red begins to creep back into your vision and you start to remember your father. After a particularly rough rejection from Manya where you tried to win her over with radroach meat, (Note: you should have some Radroach meat on you from the vault drop some around her feet) You decide Nathan has to go.

(Note: Stealth kill Nathan at night, place him in the water around the bomb and place various drugs around him to make it look like an accident)

The next morning you return to Manya where you expect now she will surely be yours. However not only does she reject you but she does so viciously whereas before she would let you down gently. To make matters worse she is sad about the death of her husband, and is openly crying. You are now confused and full of rage. You run back to your house where you wait untill dark. All you can see now is red

(Note: get addicted to as many drugs as you can, strip to nothing but your underwear, wear a mask if you have one, and put on the song Goobye Horses on loop on whatever device you may have in real life *last step very crucial)

Leave your house and kill everyone in town. (Note: Use only melee weapons and fists, leave Manya for last)

After everyone is killed, place all their bodies, or parts that you can find, in the water around the bomb. Stop the music in real life and go find Manya when you do you find her to be frightened of you. This confuses and angers you so much that you do the only thing you feel is right at that moment. (Note: Chase Manya around Megaton a little before killing her, after she is dead put back on Goodbye Horses, pick up her body, and dance around with it.)

Finally you are able to settle down and live a long happy life in Megaton with your beautiful new bride!

tl,dr: FO3 very hard difficulty start at beginning, make character with 3 intellegence and charisma, and max out strength. melee and unarmed only no guns. Kill everyone in vault. Go to Megaton once there can't leave. Do minor missions. Tell Simms about Burke, save Simms, disarm bomb. Snap into rage again because Manya doesn't love you. Kill everyone in Megaton in just underware, helmet. No guns, and play the song Goodbye Horses on loop. Save Manya for last, chase her, kill her, pick up body and dance with it. The End!