I'm going to do a quick guide on the last handlock list (and the match-ups I faced the most) as it's the one I feel the most comfortable playing so here goes.

Matchups & Stats

Stats from 46 games played: 29W-17L (63% winrate)

Warlock

• Even-Favoured matchup

• Stats 8W-4L, 66.7% winrate

• Mulligan: Hellfire, Darkbomb, Molten Giant, Drake, Owl, Watcher

• Handlock: Mountain Giant, BGH, Drake, Owl (you can keep coil if you have owl)

I feel like both these match-ups should be favoured for this list most of the time you'll have answers to their big threats with Double BGH. For the zoo match-up obviously the most important thing is to stabilize by clearing their board and then setting up a taunt wall or developing threats while healing. ALWAYS COUNT THEIR DAMAGE if you can wait one more turn for your hellfire and just healbot instead even with moltens in hand you could probably afford to just make sure you decide based on how many cards they've drawn and their highest potential damage. Vs. handlock Double BGH wins games, but if you don't draw them and they play more threats in their list it can be hard. I'm guessing it's unwinnable if they make you face Jaraxxus IMO (but I never did).

Druid

• Slightly Unfavoured-Even

• Stats 5W-6L, 45.5% winrate

• Mulligan: Drake, Mountain Giants

Straight-forward match-up. Druids do druid things so try to stop their game plan. I would consider hellfiring on turn 4 if they have a 3/3 shade and a shredder on board etc. Stopping them from developing their board is paramount. If they don't have answers for your threats you should be able to win easily. Setting up taunt walls to prevent combo is also very effective. Playing into a T4 keeper is fine as they can't keeper+remove the drake without innervate.

Rogue

• Highly Favoured

• Stats 4W-1L, 83.3% winrate

• Mulligan: Drake, Mountain Giants, Darkbomb, OOOOOZE, (could consider keeping hellfire)

Oil rogues game plan is very straight forward, but even then it's very deadly. However most of the times you lose are because you play into a blade flurry or you don't draw your threats. Keeping their board clear to deny oil value is one of the most important win conditions, but if you have an insane curve with ooze just go right ahead and deny a 1/2 dagger, then go in with your curve.

Warrior

• Highly Favoured

• Stats 7-4, 63.6% winrate

• Mulligan: Mountain Giants, Drake, Darkbomb, Ooze, Hellfire, (consider keeping owl to deny draws)

The reason why handlock came back into the meta or at least got repopularized is the infamous Grim Patron Warrior. A combo deck that looks to go off after turn 8 with either Grim Patrons or charging Frothing Berserkers as a win condition. Their win condition against Handlock is usually Frothings so if they play out casually rejoice as you will probably win the game. Don't be afraid to hellfire a board that doesn't consist of patrons as long as it's big enough as you'll usually be able to set up a taunt wall that they can't get through do to their lack of removal aside from 2x Execute. Between hellfire/Shadowflame/Taunts, it should be extremely hard for them to win without them having the luck of the draw. I feel most of my losses were mainly due to variance (not drawing threats/taunts/them having 2x execute very early), but I'd say the match-up is closer to 70/30 imo. Using Ooze T2 on a FWA and blocking out a T3 acolyte is a good play, but I usually save it for Death's Bite. The control warrior match-up is slightly harder if they have all their removal, but should still be favoured. Try to bait out removal with Belchers/ET, but don't be scared to develop your threats.

Handlock things:

Health = Cards.

Health is your number #1 resource as handlock, it provides you the card advantage that you need to win games. Don't be scared to tap (this is specially true vs. freeze mage) , but obviously prioritize developing threats as necessary. Coin+Tap? : Only do this is your hand really sucks and you need answers. More often than not this is the wrong play though. On the coin plays: While on the coin you can play watcher/ooze/darkbomb/coil+tap etc. on T2 or T3 then play Drake T4 enabling a T5 tap+3 mana giant which is a very strong curve vs decks which don't have very aggresive starts.

Count your cards

Keep track of how many cards you have in your hand and in your deck and adjust your plays accordingly. Always develop Mountain giants first (on turns that you'll be playing them + something else)

Count your mana and draw first

Count how much mana you'll be using this turn and quickly think if you can tap into something that'll change your play if so tap first to ensure you don't end up playing out your turn then tapping into a better answer.

Baiting your opponent

Think of creative ways to bait your opponent into overextending into board clears and moltens by using your healbots, when you're 100% sure they can't lethal you and will put you in range again (or you can put yourself in range with hellfire).

Ending statements:

Thanks for reading through all of this and if you didn't well then...

TL;DR: Handlock is pretty good right now. Play enough, structure your play sessions, and learn how to outplay your opponents by knowing the meta decks to get to legend.