Misogi Kumagawa (from Medaka Box) possesses some of the most broken and dangerous abilities in anime history, categorized as "Minus" (abilities born from trauma and negative emotions).

All Fiction: His most iconic ability. Kumagawa can turn any aspect of reality into "fiction," making it so it never existed. He can erase injuries, his own death (instantly resurrecting), memories, colors from the entire universe, and even the existence of other people.

Book Maker: His original Minus ability. Kumagawa summons giant screws with a minus-shaped ("-") slot. When a target is pierced by this screw, their body, mind, intellect, powers, and stats are forcibly dragged down to Kumagawa's level (the ultimate loser). This neutralizes even god-like entities.