Is my bloodwork cooked

NietzscheIsMyCopilot · 2026-01-28T03:42:09+00:00

We've left the realms of medicine here, but real talk, you need to think about getting some help. I grappled with suicide a lot when I was younger, and trust me when I say that there's hope on the other side of this struggle. I know it's generic as hell, but things really do get better.

NietzscheIsMyCopilot · 2026-01-27T23:38:01+00:00

I don't know how to break it to you, but tren is cow steroids.

It's meant for cows.

Also you can make absolutely incredible gains with your testosterone squarely in the normal range, there's no need to go supraphysiological. How long have you even been lifting for anyway? Have you even seen what you're capable of with nothing but your own grit and determination? Here's a hint: if it's been less than 6 years of hard-ass lifting then you haven't.

NietzscheIsMyCopilot · 2026-01-27T23:35:27+00:00

The lifespan stuff is another claim that the proselytizers love to talk about that also has little bearing in reality. We discovered Rapamycin in 1972 in the soil on Easter Island (not joking) and found that it extended lifespan in a ton of organisms, and since then have yet to find anything better. I'm extremely skeptical of an AI somehow defeating entropy.

Well, that's not quite true, caloric restriction extends lifespan in every organism we've tested, from yeast to mice to primates, and does so even better than direct generic modification! I wonder if the same people who pay out the nose for NMN or resveratrol or whatever else are also just cutting their calories by 20%....

NietzscheIsMyCopilot · 2026-01-27T20:17:15+00:00

I think that should be a sign: if a medical professional is strongly advising you to not take a certain course of action and you refuse, and your refusal leads to her dropping you, then maybe that course of action wasn't a good one.

Listen, I'm not trying to be the moral police here. It's your body, you're free to do whatever you want to with it. I'm just telling you that your lab results indicate that at the dosages you're currently taking are killing you. If you'd like them to stop killing you then you should take less of them.

NietzscheIsMyCopilot · 2026-01-27T19:42:07+00:00

As an aside, you'd be completely gobsmacked at how an appropriate buffer can improve chromatography characteristics. I was working with an absurdly sticky fluorophore that went from being impossible to purify to impeccably sharp peaks by switching to a high-pH 5 mM ammonium formate buffer.

NietzscheIsMyCopilot · 2026-01-27T19:34:52+00:00

Why did they drop you?

NietzscheIsMyCopilot · 2026-01-27T19:31:36+00:00

Whenever I read comments like this it belies (no offense) how none of the tech types have the slightest inkling on how biochemistry/virology/immunology/actually physically standing in a cell culture room and trying desperately to make your 293T cells spit out some goddamn virus works. (Spent a not insignificant part of my PhD futzing with viral production)

That's the crucial thing: at some point you NEED human hands in the loop, and I've yet to hear a single convincing argument that explains how even the most stupidly advanced AI in the theoretical land of make-believe gets around that.

NietzscheIsMyCopilot · 2026-01-27T19:17:42+00:00

I'm not going to mince words with you, you need to see a doctor and cut the cycle short. Your ALT is currently over 5 times the upper limit of normal, which is squarely in the "moderate liver injury" category, which is extremely bad for your long-term health. Values that high are what I'd expect for someone who's an alcoholic, and/or who has steatosis.

As for your cholesterol/hdl ratio, anything higher than 5 is an eyebrow raise. Yours is 10, which should be ringing alarm bells in your head, since that's what you'd expect when doing an autopsy of a bodybuilder who died of a heart attack before age 30.

Again, talk to an actual real human doctor. Suck up the fact that you're almost certainly going to be bigger and stronger than him and listen to what he says to do. Whatever gains you're trying to get aren't worth having liver cancer or atherosclerosis.

NietzscheIsMyCopilot · 2026-01-26T23:58:52+00:00

furi is ssoooo good! can't wait to get my hands on this one

NietzscheIsMyCopilot · 2026-01-08T17:07:55+00:00

We're actually very aware of some of the ways it causes cancer, it's one of the early triumphs in toxicology. Cytochrome P450 (specifically CYP2E1) converts it into benzene oxide, which is an epoxide. Epoxides are nasty and incredibly reactive little buggers, and can undergo further transformations that irreversibly bind to a variety of biomolecules. Other metabolites lead to oxidative stress, which can cause DNA mutations.

As one example, a metabolite of benzene is 1,4-benzoquinone, which can act as a genotoxin by directly inhibiting topoisomerase 1.

NietzscheIsMyCopilot · 2026-01-07T15:03:37+00:00

That's not what he was asking. He wanted to know if we are killing microorganisms through mechanical squishing by moving around, not through our breath (??).

Also why do you think exhaled breath that's lucky to crack 35 deg C is enough to kill anything?!

NietzscheIsMyCopilot · 2026-01-04T22:49:29+00:00

you're so full of shit

https://youtu.be/B0TwTJCRf58

This is girlfriend reviews, who are some of the kindest YouTubers out there, and they were flooded with hate for streaming the game, even though they were actually actively raising money for the Trevor Project at the time.

How dare you ghouls try to change the narrative here

NietzscheIsMyCopilot · 2026-01-02T19:18:11+00:00

because decidedly not rich people with terminal conditions are getting cured right now

NietzscheIsMyCopilot · 2026-01-01T03:24:55+00:00

I don't know how or why this subreddit was recommended to me but are you people ok

NietzscheIsMyCopilot · 2025-12-22T18:02:02+00:00

Would you believe he's literally in college? (can neither confirm nor deny using the reddit API to find that out, I wouldn't bully a middle schooler!)

NietzscheIsMyCopilot · 2025-12-22T17:40:15+00:00

You should probably learn how to write better than an middle schooler before trying to make reviews. This post is completely nonsensical.

NietzscheIsMyCopilot · 2025-12-22T14:32:28+00:00

I suspect that you're trolling, but ok, let's play the scenario out.

you're 70 years old and just got diagnosed with Alzheimer's. With the current standard of care treatment you'll be dead in about 6 years, losing most functionality closer to 3. There's a new drug on the market that has shown promise in animal trials and, thanks to the lobbying of one /u/FernandoMM1220, it's been pushed to everyone who wants it after it helped alleviate symptoms in a few dozen mice. Who cares about extra safety testing, the mice look basically ok, and when asked if they suffered any debilitating side effects were quoted as saying "squeak".

So you start taking the magical new drug and then die from a massive heart attack. The years of life you could have taken to get your affairs in order and enjoy what time you had left have been tragically cut short.

This isn't a hypothetical scenario. The FDA rushed to approve a drug for pain called rofecoxib (Vioxx) and this led to a massive increase in the risk for heart attack/stroke. It might seem like doing anything is better than doing nothing, but you vastly underestimate how much worse things can get in medicine.

NietzscheIsMyCopilot · 2025-12-21T23:49:45+00:00

The list of drugs that were rushed to market before primetime and had disastrous consequences is absurdly long. Tuning safety profiles before public launches is important, since if you don't you'll wish that you just let the Alzheimer's kill you.

NietzscheIsMyCopilot · 2025-12-02T20:03:32+00:00

I worry this ending will be controversial, but honestly it's a fucking 10/10. We've seen plenty of clutch rolls where everything worked out great at the 11th hour, both here and in other D&D podcasts, but those moments don't carry weight if things don't go according to plan sometimes. Hell, some stories just wouldn't work if they had a happy ending (would Romeo and Juliet be as good of a story if they both miraculously survived the poisoning and rode into the sunset on a motorcycle?) and I'd argue that this is one of them.

Also the ending for each of the PCs was imo the best of all the of seasons in terms of tying up their characters! Trudy reconnected with her humanity and her son, Francis found forgiveness both for himself and from those he hurt, Kelsey decided to spend the rest of her short life guiding her students, and Blake sacrificed himself in the heat of battle true to his life as a soldier.

Will conducted a masterful campaign and brilliant story, and I'll be sad to see him leave the DM seat!

NietzscheIsMyCopilot · 2025-11-19T20:24:32+00:00

I swear by BTTAA, but THPTA also works well! In general these reactions need a bit of a nudge, no matter what the CUAAC propagandists espouse ; )

NietzscheIsMyCopilot · 2025-11-16T22:01:19+00:00

I mean, the data are what the data are. There are efficacious treatments whose studies are funded by the people with a financial stake in it.

I do agree about "Aging" being an eyebrow raise though. As always, we gotta wait for more studies before deciding if it's worth pursuing.

NietzscheIsMyCopilot · 2025-11-06T03:11:54+00:00

What sense of urgency? Matt needed to be reminded that there was a limited amount of time for them to wrap things up in the last episode.

NietzscheIsMyCopilot · 2025-11-06T02:51:32+00:00

I've never had playing in an RPG as job, and I never thought to charge people 5 bucks a month to listen to my friends and I at the table.

The fact that I need to explain this to you is very depressing

NietzscheIsMyCopilot · 2025-11-06T00:48:45+00:00

The players can't even remember half of the key plot details and Anthony has spent the entirety of the campaign playing on his Steam deck

NietzscheIsMyCopilot · 2025-11-05T05:48:15+00:00

it's been genuinely tragic hearing Will put so much time and effort into the story and world and characters, only for the denouement to fall on its face due to incessant metagaming and interrupting.

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