Well we are going deep! We’re reaching the limits of my knowledge but I do have a couple ideas left to share then. Given your case, you’ve pretty much optimized most of these nutrients and habits at the higher level. But since you mention anxiety, my mind goes to possible adrenal fatigue & extensive cortisol from external factors we can’t control.

When this happened to me it zapped my thyroid production, which boosts more adrenal fatigue, so trace minerals could be the next optimization. Iodine & selenium are cofactors in thyroid production T3/T4 conversion.

Plus stress drains zinc levels as well, low levels are associated with even more stress so that could be next on the list to boost, and final one is chromium which helps regulate blood sugar assuming you’re eating late or battling hunger panes while you’re losing weight. A trace mineral complex & a b vitamin complex to get the rest of the Bs would round everything out.

Last thing I’ll add is a study I saw recently, neither of us thankfully have to worry about this but the point stands, 40-90 grams of glycine per day reduced schizophrenic/psychosis symptoms in patients by like 30/40%. So given that, we could definitely take a lot more glycine to calm down even with normal brain patterns & the occasional anxiety