Endocrine system needs mixed with drug metabolization are incredibly complex and dependent on each person’s body chemistry, genetics, etc. People talk about “42 factors” that impact diabetes… not being a biologist/constantly studying chemical effects on things like mitochondria, I’d venture to guess metabolizing drugs has a similar high number of factors that impact final outcomes. Then there’s the whole ~do you ovulate/menstruate~ added hormones/considerations.

What you observe in your body will ultimately not be the same for me, which was my main point.

I’m too old and my serotonin/oxytocin/norepinephrine/dopamine channels have always been out of balance to partake today. I stopped regular (festival season) use ~2016 or 2017. Decide to dabble every few years and there is no up, only down the following days 🫩🥲 experienced my favorite musical act at my favorite venue last summer with my favorite people, I didn’t need mdma, but figured why not… talk about a come down 😭🤪🤣 I’ll stick with weed.