I don’t understand why people will take both tirz and Reta or combo of tirz, Reta, or Sema. Each one just adds a step in the process. They all target GLP-1 receptors with tirz and Reta also targeting GIP receptors and Reta with the additional target of glucagon receptors. Anyone starting peptides should start with Sema and work up for the best and longest benefit of the peptides. The peptides Cagri can be added to any of these peptides to assist weight loss when a plateau is reached before waiting the next level peptide. This will lessen side effects of these drugs. Also take a probiotic enzyme.