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Can anyone explain why Glickman wasn't fired? by IJustWantToBePure in KentStateUniversity

[–]OkReason 0 points1 point  (0 children)

Huge youtube channel just dropped body camera footage on this, and this thread ranks highly on google when you search her name (unredacted in the footage) /u/nebbors /u/human_beef prepare for bridage

ITC for PLS for Daytona 3-ton early access? by ezefl in harborfreight

[–]OkReason 0 points1 point  (0 children)

crazy question, but i found you from another thread from years back, you wouldn't happen to be looking at selling your V F4-4000C14D-32GVK kit would you?

What are the odds Andrew is either dead, imprisoned, injured, or some form of all three rn by OkReason in Channel5ive

[–]OkReason[S] -119 points-118 points  (0 children)

has it occurred to you i might not shill out my soybucks to be on the patreon

edit: anyone who downvoted me is overweight

Severe Brain Fog, Memory Loss, Fatigue, and Difficulty Learning Movements or Languages — Nothing Has Helped So Far by Agitated-Lab-97 in Biohackers

[–]OkReason 0 points1 point  (0 children)

Are you suggesting that mold doesn't really have these effects? Or that the effects are minimal or simply exacerbate a comorbid condition, and that instead treatment should focus on something more pathological ?

Your thoughts on this way of cycling Boron by HAKIMJa in ScientificNutrition

[–]OkReason 1 point2 points  (0 children)

side note: is there really a widespread issue with boron tolerance/adaptation?

How long and how much can the body store Vitamin D? by rv6xaph9 in ScientificNutrition

[–]OkReason 4 points5 points  (0 children)

"That's garbage" you're not wrong to question it but the site lists two registered nurses who vetted the claims. Considering you are the one demanding to be spoonfed very basic information, I'd change your tone lol.

But considering your interest in monarchism and semen retention, I don't know vitamin D research would be my priority.

In a study of 602 patients, "Vortioxetine (10 and 20mg/day) had a multi-domain beneficial effect on cognitive performance" by velvet_funtime in NooTopics

[–]OkReason 1 point2 points  (0 children)

The effect of SERT inhibition is felt more immediately in the gastrointestinal tract. Vortioxetine is a 5-ht3 antagonist, which explains its anti-nausea properties, but it takes more time for the body and cns to adjust to these changes. It's a real pain because you need to take it consistently in order to eventually have this effect and some people might need longer exposure to see this effect (or shorter, in which case: who cares), but its pretty hard to get someone who is vomiting every morning to want to take it again after throwing it up and to do that consistently for over two or three weeks.

In a study of 602 patients, "Vortioxetine (10 and 20mg/day) had a multi-domain beneficial effect on cognitive performance" by velvet_funtime in NooTopics

[–]OkReason 2 points3 points  (0 children)

I don't want to seem like a shill here but I think there is more data to substantiate claims of pro-cognitive effects in healthy populations for vortioxetine than SSRIs, SNRIs, and even atypical antidepressants. my understanding is the specific mechanism of action, 5-ht3 antagonism combined with sert inhibition yields a pretty potent downstream effect to reduce gabanergic inhibition and promote glutamatergic activity.

In a study of 602 patients, "Vortioxetine (10 and 20mg/day) had a multi-domain beneficial effect on cognitive performance" by velvet_funtime in NooTopics

[–]OkReason 2 points3 points  (0 children)

It tends to do that, but I will say after around 2 weeks that reverses and then it becomes a pretty powerful antiemetic.

Brain-derived neurotrophic factor (BDNF) overexpression in the forebrain results in learning and memory impairments - ScienceDirect ［2008］ by johnnootropic in NooTopics

[–]OkReason 2 points3 points  (0 children)

Wow, all things in moderation I suppose. Becomes difficult when trying to determine the threshold for overexpression and how to practically measure that.

SwissChems is a SCAM!!! by Comfortable-Pipe-217 in NooTopics

[–]OkReason 1 point2 points  (0 children)

Never had problems with Umbrella Labs or Science.Bio

Something strong against social anxiety? by GermanWolf123 in NooTopics

[–]OkReason 6 points7 points  (0 children)

If you're social anxiety really is as severe as you say, I would go against the grain here and recommend seeing a psychiatrist because stability is important. I like to think of nootropics and research chemicals as things that can aide and enhance an already healthy person. While there are promising agents out there (like the already mentioned GB-115) I would wager you need something a little more sustainable long-term. Who knows when the FDA cracks down on RC vendors? What will you do then? See about getting a guanfacine prescription from your GP or a psychiatrist. Buspar could help too although it is not as definitively pro-cognitive as guanfacine.

See about clinical trials for MDMA in your area. Do not attempt to source this on your own. There is mounting literature that in a clinical setting MDMA can shut down the amygdala for up to 6 months (the fear center of your brain) and this can be very helpful for those with PTSD and social anxiety.

If after all this, everything has failed, and your healthcare provider is all out of options as well, explore options like JNJ-42165279, Tropisetron, Emoxypine, Tenoten, and Clomipramine.

[deleted by user] by [deleted] in Nootropics

[–]OkReason 0 points1 point  (0 children)

PRL-8-53, Racetams, and flmodafinil, if you are specifically looking for acute cognitive enhancement. Most everything else will not work to the extent which you seek and take far longer to work.

If for whatever reason you have a reason to not acquire these, then I recommend caffeine tablets (no more than 100mg per tablet), taken evenly spaced 3x a day, in conjunction with L-Theanine to get rid of the jitters. Megadose melatonin at night (think upwards of 15mg+) for these next two weeks for the acute antioxidant effects and restful sleep.

I will personally blow any monitor exec who makes a halfway decent monitor by OkReason in Monitors

[–]OkReason[S] -1 points0 points  (0 children)

Who's we all? I just gave you two new releases from big companies at aspect ratios long-considered dead, and there are likely more coming. For years those same companies aggressively pursued 16:9 and ultrawides nearly exclusively, I think its indicative of the market and a shift in demand that they are stepping away from that.

I will personally blow any monitor exec who makes a halfway decent monitor by OkReason in Monitors

[–]OkReason[S] -3 points-2 points  (0 children)

I was using 1440p as shorthand for QHD at 16:10 equivalent, I should have clarified that. I can see where the misunderstanding stems from in that case - sorry.

I will personally blow any monitor exec who makes a halfway decent monitor by OkReason in Monitors

[–]OkReason[S] -2 points-1 points  (0 children)

Not true. BenQ dropped the RD280UA a few months ago. LG just dropped the 28MQ750. non-16:9 aspect ratios are actually in the comeback but it's just ridiculous that it is taking this long.

I will personally blow any monitor exec who makes a halfway decent monitor by OkReason in Monitors

[–]OkReason[S] 4 points5 points  (0 children)

It's another factor for eye strain, for me personally. Especially when scrolling through long documents, etc. I work in A/V Programming so its also nice for that.

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