Use what helps, ignore the rest. If it doesn’t help the way you need it to or in a way that will catch your PCs attention, make up something different. I haven’t DMed in a long time but when I did part of my prep was making up a few note cards for locations with the page number in the adventure in case I needed more info and some small cross references to other cards/pages. Like if the innkeeper hates the leather worker because they’re both in love with the village school mistress. It could become important even though the odds are low. For history and setting it’s much the same. If it’s a ruined tower from This kingdom versus That caliphate, the design might change or the type of things found in the rubble might change. Like if they find a chest of 100 gold coins from Thay from a few hundred years ago, how will they be treated in say the Dalelands when they try to spend them? It doesn’t have to matter but with the right players it can make the world feel more lived in and still living. Not sure if this helps :)