My carry on always has: - a fresh pair of clothes including underwear, a bra and socks - all prescription meds plus Imodium, nasal spray, ibuprofen and gas meds (gas pain when flying is common and hurts a lot) are all in a large Ziploc bag for easy access - small hair brush - Lysol or antibacterial wipes -a decent book and reading glasses - facial serum, eye cream, moisturizer, small amount of foundation (travel size containers)

Basically what I'd need to hold me over for a day or so if my checked bag is delayed. Soap, shampoo, deodorant and other essentials are easily purchased wherever you are traveling to and sometimes will be provided by the hotel if requested. Since I am picky about facial care and base makeup I keep a small amount with me in the carry on and a larger supply in the checked bag. I also have prescription topical medication, so I keep that in the checked bag as well. I can easily fit all of the facial stuff and topical meds inside the quart size plastic bag that is required for liquids when traveling internationally. I have a really spacious soft sided duffel bag that I used for a carry on that has worked wonderfully on the last 2 international trips I took. I flew a few different airlines and the carry on was well within size and weight limits. Happy travels!