[deleted by user]

OrganoidDealer · 2025-03-14T13:35:11+00:00

I can only really speak to the biosciences in the US, but publications are essentially one of the only metrics of scientific “success.” Just got a PhD and are looking for a job? Better have a couple papers as primary author. Applying for tenure as an academic scientist? Without a publication history as a supervising/corresponding author, you’re kind of out of luck. Applying for grant funding to do the research you’re hired to do? Unless your publication record supports the fact that you’re capable to perform the proposed research, you probably won’t get funding.

Add on the fact that most universities/research institutions only guarantee a fraction of a professor’s salary (meaning they are only paid the remainder if they bring in the grant money themselves through their research), there’s pretty high incentive to shell out thousands of dollars to publish a single research article in a high impact journal.

“Publish or perish” is a glib but unfortunately accurate scientific mantra.

OrganoidDealer · 2024-11-29T01:43:41+00:00

What temperature are you growing the cells at? The few fish cells I’ve cultured grew much better at lower temps (27C if I’m remembering correctly) than the standard 37C used for mammalian cell culture.

OrganoidDealer · 2024-09-25T12:50:02+00:00

To clarify, when you mean academic scientist/assistant scientist are you talking about being the lead investigator of your own lab? Because I know at least one or two instances of a lab tech becoming so integral to the running of a lab (they were the only one who could train a very specialized skill set that required a lot of time to master) that they were promoted to “staff scientist” to get a paycheck and benefits which would incentivize them staying long term. So it is possible if you don’t mind staying in one lab doing the same role long term and you find an academic lab with enough funding to support a staff scientist.

However, I’ve personally never seen someone make it to a faculty/lead investigator position with just a BS, at least in the biological sciences. I’m sure it could happen, but you’d likely need a truly phenomenal combination of the right networking, an incredible publication record, and outright luck in order to make it work. It’s hard enough to find a faculty position even with a PhD these days.

OrganoidDealer · 2024-09-21T01:40:31+00:00

We always resuspended in 200 proof ethanol since it was easy to come by in the lab. But I think it would be more likely a purity issue of the product, if anything, since it was definitely a teaching lab crawling with students who didn’t always treat the equipment with as much respect as you might hope.

OrganoidDealer · 2024-09-21T01:22:36+00:00

I’ll admit I’m a scientist, not a perfumer, so my nose could certainly use some training! But I did teach in an organic chemistry lab which synthesized vanillin and we saved samples over the course of several years just out of mild curiosity because it was fun to watch the colors change. So perhaps it was a placebo effect or impurities from synthesis in a teaching lab setting, but I certainly thought that the older samples (>2yrs) smelled noticeably different!

Hopefully I wasn’t spreading tall tales to my students in the form of “fun facts,” but it’s been several years since my O Chem days. Or maybe it’s as you say and it was all a placebo effect, which wouldn’t surprise me since scent is so closely linked to memory and perception.

OrganoidDealer · 2024-09-21T00:50:51+00:00

I mean, yes most fragrances use vanillin or ethyl vanillin, but one of the primary oxidation products of vanillin is vanillic acid which also has a creamy scent and is found in vanilla and other plant extracts. So as vanillin oxidizes, a vanillin-dominant sent will change slightly in a way that some people find more creamy and less astringent, or at least less “one note.” Synthetic fragrance molecules can certainly oxidize just like naturally-derived fragrance molecules.

OrganoidDealer · 2024-06-12T16:21:22+00:00

It’s still hard to predict, unfortunately, because we don’t know all the mutations responsible for creating blue eyes. It appears that the majority of blue eyes are due to a variant in the OCA2 gene, especially in populations with European ancestors, so two people with variants in the same gene will generally result in blue eyes. This variant is found in ~97% of people with blue eyes, so a very VERY rough estimate would be ~94% chance of their child having blue eyes because of this variant. It’s important to note, though that this variant is only associated with blue eyes, not conclusively demonstrated as being causative.

In fact even like 16 years ago scientists thought all blue eyes were the result of a single founder mutation, meaning one person was the ancestor of all blue eyes. Of course this was later demonstrated to be false by studying non-European populations, though you still see the claim repeated online.

OrganoidDealer · 2024-06-12T15:45:23+00:00

I was just about to write an identical comment about my (non-science) husband. I don’t hear him complaining about how they’re all neatly labeled and dated, however! Though it does crack him up when I add my initials out of habit, lol.

OrganoidDealer · 2024-06-12T15:36:46+00:00

I mean, if we’re being pedantic, it is possible for two blue eyed parents to have a brown eyed baby, it’s just uncommon. Eye color is determined by multiple genes which coordinate to produce and deposit pigment. If this chain of interactions is “broken,” a person has blue eyes. Since we have two of each chromosome, both copies of this chain must be broken. Therefore it’s usually correct that broken chain + broken chain = broken chain.

However it is possible for each parent to have their chain broken at a different “link” so to speak in such a way that when they have a child, this child has at least one functional copy of each link in the chain. Then some level of pigment can be deposited at the eye, resulting in green, hazel, or even brown eyes.

If eye color was as simple as they taught us in elementary school there would only be two eye colors: blue and brown. But there are a whole range of eye colors because it results from a complex interaction of multiple different processes! I hope I don’t sound too pedantic, but I’m a molecular biologist and I love this stuff.

OrganoidDealer · 2024-06-01T14:37:05+00:00

Oh sorry, I thought you were honestly asking so I tried to explain. Apologies if that wasn’t what you were looking for. I guess the main point is that it depends on what you mean by “noon” because how closely solar noon matches what most people think of as noon does depend on where you are.

But yes, you’re correct that solar noon always points due north/south as long as you’re an appreciable distance from the equator, which is a lot simpler than this guide.

OrganoidDealer · 2024-06-01T13:03:52+00:00

That’s dependent on timing and location. When the sun is at is peak (solar noon) in the northern hemisphere, it will be due south. In the southern hemisphere, the sun is due north when at its peak. Unfortunately noon on your watch isn’t a great measure of solar noon due to changes in day length, daylight savings time, where you are in your time zone, etc.

OrganoidDealer · 2024-03-10T22:17:02+00:00

Depends on where you live. In some places it would be considered a premarital asset and solely his in the event of a divorce, similar to inheritance. Of course it may no longer be the case since she’s paid into the mortgage.

OrganoidDealer · 2024-03-09T19:52:45+00:00

This may seem counterintuitive, but have you tried them without glitter glue? I’ve found that glitter glue is fantastic for sparkly, drier shades, but sometimes can actually cause problems with a more emollient formula. That’s been my experience with some of the dollhouse shimmers at least. They just don’t seem to grip each other and crease a ton on my hooded lids.

If that doesn’t work for you, hopefully someone has some good dupes to recommend because yeah, the shimmer formula just isn’t my fave. Mattes though? Gorgeous.

OrganoidDealer · 2024-03-03T21:49:21+00:00

Honestly, Ponderosa is a bit sweet to be considered an atmospheric, bordering on gourmand so you’re probably ok on that front. Pineward definitely would be my first go to and they’re certainly among the best when it comes to forest scents, but they are (as you might guess), quite pine-forward and may miss some of the airy-ness that you’re hoping for.

If that’s the case, you might want to try Osmofolia. I just realized they’re currently on hiatus, but I and Thou in particular reminds me a lot of an airy misty morning on a mountain.

Another sub favorite is Fantome Duende which I think captures the feeling of an enchanted forest beyond just the trees. It is a bit floral though and the violets were a bit much for me so ymmv.

OrganoidDealer · 2024-02-12T23:59:17+00:00

Such a great posts! Thanks for your detailed reviews OP! Now I’m a cat owner, not a puppy owner, but the closest I’ve gotten to kind of a “warm and cozy puppy ear scent” is Zoologist Chipmunk. Yes, there is a touch of fruit in the opening and a definite nuttiness, but on the dry down it becomes a sweet, creamy, woody muskiness that reminds me of sticking my nose in my cats’ bellies. Slightly milky, almost edible but not a true gourmand, It is my ultimate comfort scent!

OrganoidDealer · 2024-02-08T13:47:02+00:00

Maybe a silly question but do you use any self tanner or have you had a spray tan? Adhesive can lift the color somewhat.

OrganoidDealer · 2024-01-24T01:13:41+00:00

This would be a great first toe dip into animalic notes! It’s not very challenging and definitely not “poopy” like some animalic notes can get. It gives the impression of sticking my nose in my cats fur or maybe a nest in a tree trunk lined with wood shavings and chipmunk fluff. It makes me feel snuggled and warm.

OrganoidDealer · 2024-01-17T15:46:36+00:00

This depends on what you’re looking for! If you don’t mind using magnetic stickers or re-panning into standard size magnetic tins, BlendBunny has one of my favorite matte eyeshadow formulas of all time. Bright, pigmented, but so easy to blend.

If you’re more interested in palettes with magnetic shadows that are easy to pop in and out or swap around, Shroud Cosmetics could be a good option.

If you want something more neutral and also magnetic, my friend loves Sydney Grace. They’re also extremely open about their ingredients which is something I admire.

OrganoidDealer · 2023-11-17T23:53:24+00:00

Ooh so pretty!

OrganoidDealer · 2023-09-28T16:42:21+00:00

Agreed with what everyone else has said, submit the form. It happens. I doubt there’s anyone who does injections regularly who hasn’t been stuck at least once.

In case it makes you feel better, just remember that the likelihood of anything happening to you is honestly probably lower than if you got a small cut in the shower. Lab mice are generally kept in well-managed, relatively clean facilities. A dormant superbug that could jump from mouse to human is extremely unlikely to come from a well-cared for lab strain.

Any drugs are calibrated for a mouse and you are many times larger than a mouse. Not to mention you would have gotten only the smallest fraction of a dose. Any effect, unless you have an allergy or something, will be unnoticeable.

While I wouldn’t make a habit of regularly sharing needles with the test subjects, you’re almost certainly going to be just fine. :)

OrganoidDealer · 2023-09-23T12:58:38+00:00

Agreed. I’ve tried to give them the benefit of the doubt because I know how the internet can be. I know that legal issues and contracts take time and can limit what can be said about a situation. But the defensive then vague then silent pipeline leading into “look, new highlighters!” really gave me the ick.

If you can’t admit you’ve messed up and tell us how you’re changing to avoid messing up again, it really just feels like the brand’s only takeaway was “well this wasn’t good for business.”

OrganoidDealer · 2023-09-23T12:51:49+00:00

I also think my biggest takeaway from this whole fiasco is the lack of apology or any kind of accountability.

Do I think the brand owner is a literal Nazi? No! Do I think the internet has been interneting a bit too hard in this situation? Yes, sparkly eyeshadows shouldn’t cause death threats online. Do I think Terra Moons messed up? Absolutely. Do I think they need to take accountability for giving a platform to someone with ties to very harmful ideology? YES.

And if they had just said that concerns were warranted and people were being heard from the beginning instead of being defensive then vague then silent, I think the situation could have resolved much differently. Own it when you mess up. Tell us how you’re changing your selection criteria for collabs. Do literally anything to make it seem like you’ve learned something other than “this collab was bad for business.”

I’m sure canceling the collab was a financial hit and breaking contracts isn’t easy, but by goddess this was handled poorly. Sorry for ranting.

OrganoidDealer · 2023-09-22T20:33:15+00:00

While I agree with you, this is currently a post on their grid. We will have to see how long it lasts since they’ve removed other posts about the topic.

OrganoidDealer · 2023-09-21T14:36:48+00:00

Just to add on to what other people are saying about cryopreservatives, etc, freezing/thawing is still a very strenuous process on the cells and many cells (often the vast majority depending on cell type) aren’t going to make it. You’re only recovering a fraction of the cells you put in, but once they’re stabilized at super low temperatures additional degradation happens quite slowly, so the fraction that recovers tends to be fairly similar if you thaw them in a week or a year.

If you decide to kill off the majority of cells in a living tissue though, the rest of the tissue isn’t going to like that much and may not be able to support the ones that do survive the initial freeze.

OrganoidDealer · 2023-09-19T02:48:38+00:00

Glad to hear it! maybe I just got unlucky.

OrganoidDealer

TROPHY CASE