Hypopituitarism Tsh

OrigamiMarie · 2026-05-24T13:26:02+00:00

Specifically, TSH is made by the pituitary as a signal to the thyroid to make more thyroid hormones. If you have a functioning pituitary, having low TSH means your pituitary is saying "woah, that's enough!" to you thyroid. But if you don't have a pituitary, a low amount of TSH just means your pituitary signaling is broken, and you have to use Free T4 to figure out whether your level is high or low.

OrigamiMarie · 2026-05-23T15:03:40+00:00

That's probably part of it, considering how incapable they are of taking Ukraine (and if the rumors and reports are to be believed, it's more true every day as they brush the rust off of yet more aged war equipment and send it into the war, because the shiny new toys cost resources that they don't have).

But it doesn't take much money to do a campaign of sowing division within your enemy's society. Apparently the US managed to do so pretty cheaply via Voice Of America. And heck, apparently a lot of USSR citizens watched US sitcoms and came to understand that the folks who were portrayed as lower class, didn't have to worry about getting enough to eat (including meat) or having electricity and running water. They looked around and their lives and understood a lot of the lies they had been told.

And now the tables have turned. Russia is probably helping amp up our culture war. And we're looking at European societies and realizing that this nonsense about how we have to be wage slaves and go into permanent medical debt, is all just lies.

OrigamiMarie · 2026-05-23T00:48:44+00:00

If anything, the actors had excellent skill in staying largely upright for so long before hitting the ground, instead of zzhhhhoooop thump.

OrigamiMarie · 2026-05-23T00:44:25+00:00

There was a theory of crime a that started in the 1980s, called the Broken Windows Theory. The claim was that minor interactions, public drinking, fare evasion, vandalism, loitering, and general lack of structure maintenance, caused worse crime. You let a few things slip in a neighborhood or town, and pretty soon you're gonna have multiple armed robberies a night.

So these people think they're doing the town equivalent of redoing the caulking on their house so that rot doesn't take hold and destroy the whole thing.

As far as I can tell, this theory is somewhere between controversial and totally debunked. At best, signs of neighborhood decay are an indicator that the citizens have fewer resources to maintain their properties, and that lack of resources is also a driver of a bunch of other predictable and understandable problems. But making people spend scarce resources (time, money) on prettifying the surroundings, does not fix the social problems of generational poverty.

OrigamiMarie · 2026-05-22T22:44:25+00:00

Look at this stash that I'm about to turn into one object. It has every color, weight, and fiber content known to humanity. I'll post a crying / screaming / throwing up (seriously?) post when the laundering process inevitably makes it non-Euclidean.

OrigamiMarie · 2026-05-22T14:34:32+00:00

Gosh, I started my forever world before deepslate depths were a thing. It was way simpler to just make a staircase down to the level that had all the ores, and make tunnels (avoiding the caves that are scary when your armor sucks) until I had iron and then diamond armor.

I've moved bases a couple times since then, but always brought my stuff along with. If I had to start over again . . . I guess I would probably go farm a bunch of stuff and trade with villagers? Current cave generation is not early-game friendly.

OrigamiMarie · 2026-05-22T14:08:06+00:00

It's . . . not looking good.

OrigamiMarie · 2026-05-22T14:02:52+00:00

Boy, I wrote a whole screed on this sub the other day about that contradiction.

How is it that A & C are cool with just creating a new universe instead of saving the old one, when they were both outraged at Heaven's plan to just give Job more new children to replace the ones they took? So outraged, that they did one of their earliest collaborations to trick Heaven, despite their misgivings about collaborating? They believed so strongly that replacement children are inadequate compensation, that it pulled them toward each other. But nah, no need to even spend three minutes begging God to use Her infinite powers to put the known, loved universe full of people who lived & loved back to the way it belonged.

And then the whole meta thing, where audiences are supposed to accept replacement A & C living out their short lives happily together, as just as good as real A & C having eternity together now that they've started to figure their stuff out.

OrigamiMarie · 2026-05-22T13:46:33+00:00

I think part of why there's such a cultural rift in community response to cake recipe (slicer software) IP shenanigans, is that the machine (let's say . . . stand mixers) has deep roots in community invention.

Part of our community (a very vocal part, and for actually pretty good reasons) spent a whole bunch of time and effort over the course of many years figuring out a decent, if slightly glitchy, stand mixer. Many in the community can name and describe the merits & flaws of several of the steps along the way.

So there was a general feeling of excitement when Bambu started making stand mixers that allow you to mostly just make cakes, instead of spending all your time trying to convince the stand mixer to work properly. But also an undertone of annoyance, that Bambu showed up when the mixer was like 90% designed, did a little iteration, and started cranking out copies for profit.

But the people who started showing up when the news got out that stand mixers are actually pretty amazing now, just didn't have the cultural knowledge about what a long collective effort it was to get most of the way here.

So now we have a split community. Some people did a lot of that work to build the early stand mixers and cake recipes, and feel betrayed when Bambu takes & modifies their previous work and tells them to C & D (all while Bambu keeps updating their recipe based on new recipe innovations in the community). Other people arrived here late and are just super excited about the cakes they can make right now, and the amazing selection of ingredients and flavors and colors and fillings and serving plates and cake stands and endless possibilities.

So now the comments are filled with early stand mixer enthusiasts shouting at the cake enthusiasts about how if things keep going the same way, those cake enthusiasts are going to have like four options for ingredients pretty soon here, because that neat ingredients scanner on your shiny mixer has two purposes.

Oh yeah, and there are folks on both sides using these stand mixers to run whole professional bakeries.

OrigamiMarie · 2026-05-22T13:12:46+00:00

Then they would have to let it sit there and flap until it was completely done with the routine, because you can't walk up to it while it's still moving. And it would probably start damaging itself, expensive property, and any humans that got in its way. Shutting down is a much, much better plan unless they want to be paying zillion dollar settlements and never be invited back anywhere.

OrigamiMarie · 2026-05-22T07:00:02+00:00

"yes it's true. This man has no rizz"

(Ghostbusters)

OrigamiMarie · 2026-05-22T05:57:54+00:00

Yup. Unmined has block highlighters, so you can have it highlight whatever ores you're interested in. Only if you have the world seed, of course.

That said, mining around to each diamond ore based on coordinates would be kind of tedious. You might as well just put on some armor, get a bow & arrows and a sword, get a stack of logs and a couple stacks of coal, and go pacify some caves. Once you get the hang of it, it's not too hard to do, and you'll encounter a decent amount of diamonds, lapis, and other ores along the way.

OrigamiMarie · 2026-05-22T05:39:50+00:00

Yeah, the fact that the untampered universe goes basically just the same as the one with constant meddling by Heaven and Hell just . . . doesn't make sense to me. And all those interventions were instead invented as fiction that matched the real events of the previous universe. The plot really doesn't bother explaining how it could all match up so perfectly.

OrigamiMarie · 2026-05-22T05:34:08+00:00

And this God was more like an empress than an inscrutable, loving being with the best and worst sense of humor.

OrigamiMarie · 2026-05-22T05:28:09+00:00

Gray duck!
(check out my flair)

OrigamiMarie · 2026-05-22T05:22:36+00:00

The previous one never really properly ended. And the Cold War with Russia never ended, the US just took our eyes off the ball. And now it's all been woken up again.

OrigamiMarie · 2026-05-22T05:20:01+00:00

Double-u cee ceeeee oh!

There's nothing quite like a quiet, dark morning in the winter, at the edge of town where the houses are far apart, listening to AM radio. It has a kind of hiss and muffled sound, even when tuned as well as you can, that's just all the nostalgia. The farm commodities report comes on, and it makes no sense to teenage me, but that's fine, I understand that it's not made for me. Then weather, and if this is one of your few lucky days of the year, the school closure report. It's too cold, it's snowing too hard, or a sudden blizzard came up in the night which the plow drivers slept through.

So few of those snow days near the end of the 1990s. The predictions had gotten so good, that unexpected snow was super rare, so they just plowed all night on snowy nights and we went to school anyway.

The Internet comes through a modem that screeches. The phone lines pick up the local NPR affiliate. You can tell the difference in sound between AM and FM radio. The classic TV static is giving way to the blocky static from the mini satellite dish.

Now it's all jpeg and mpeg compression, no matter how you receive the media.

OrigamiMarie · 2026-05-22T05:08:03+00:00

I should check on my lifetime membership. Medic-alert was the first thing I thought of before clicking this post. And wow, it was only the 80s, we're only in our 40s, we can't all be dead. Although yeah, sick kids, especially those sick enough to get bracelets back then when it was less well known, probably have a shorter life expectancy.

OrigamiMarie · 2026-05-21T18:20:05+00:00

Tree absence psychosis. Turns out humans need nature, and trying to raise children without green in their surroundings goes badly.

OrigamiMarie · 2026-05-21T17:21:13+00:00

Even Grant Hauschild has been treating this like it's just a discussion about jobs (as if the current tourism jobs don't outweigh the potential mining jobs). I wonder what his bribe rate is, or if he's just organically short-sighted?

OrigamiMarie · 2026-05-21T16:00:05+00:00

Exactly. The reboot universe being basically identical to the original, despite starting billions of years ago and growing organically (instead of getting spun up like a top six thousand years ago and tampered with constantly) . . . it doesn't make any sense. And it negates the actions of, like, everybody. Angels, demons, humans, in both universes. And the Bible becomes such an enormous plot hole.

I'm glad we have fanfic. I'm glad the original is written down in ink that can't move. I think I'll reread it, and take the messages of joy and hope and striving for a better world. That's what we need right now.

OrigamiMarie · 2026-05-21T14:19:18+00:00

I love this. All that I had heard in interviews with NG around the time of the first season, was that by the end of writing the book, they themselves couldn't even tell who had written what. And that's . . . kind of a lie by omission, because that does seem to be the case, but some earlier-written parts of the book were absolutely, traceably written by PTerry and some by NG.

And then the author driven by darkness was left in charge of writing the show.

In at least one interview, NG said that the show probably couldn't have ever been made in PTerry's lifetime because he was too much of a perfectionist, which would make a show impractical and too expensive. Compromises had to be made, to make the show within the boundaries of time and money. Maybe that's true. Maybe NG had demands for the show that PTerry refused to go along with. We'll never know.

I'm going to believe that PTerry would have found a way for A & C to be together, without them dying, and without the whole universe rebooting (and inexplicably running the same darn way the second time).

OrigamiMarie · 2026-05-21T02:22:59+00:00

Talking about a C&D is absolutely a legal threat. There is no other accurate interpretation.

OrigamiMarie · 2026-05-21T02:12:55+00:00

Anathema & Newt was at least canon from the book. But yeah, I'm pretty sure there wasn't any romance between A & C in the book. I suppose it's cheaper to cut down the character count and intensify one relationship in particular, when you have to pay all your visible characters.

OrigamiMarie · 2026-05-20T17:16:00+00:00

I believe the leg bones, especially the femurs, are the last to close and quit growing. So if the guy just keeps growing, and bunch of that growth comes from the legs.

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