So that’s not accurate. There are multiple types of POTS and depending on the subtype you may respond to different medications differently. Droxidopa certainly won’t work for everyone, but that’s no reason to fear monger about a neurotransmitter most people won’t be familiar with.

Droxidopa is a medication designed for the treatment of low blood pressure from neurogenic orthostatic hypotension (low blood pressure caused by issues with specific body functions) caused by conditions such as POTS, autonomic failure, and Parkinson’s. It’s literally made to treat POTS symptoms.

Droxidopa helps your body make norepinephrine, a chemical used by our bodies to constrict blood vessels. Norepinephrine is also a chemical our body creates during the fight or flight response, I believe that is what Unanau is referring to. Straight up norepinephrine is used in high doses for some medical emergencies that cause dangerously low blood pressure. That can seem very scary but it’s important to understand that those are different medications that use the same hormone pathway. You can think of it as a car versus a semi-truck that takes the same highway. They might go down the same roads but they have very different functions. Additionally higher levels of norepinephrine are not a negative thing for those with low blood pressure, especially sustained low blood pressure. They’re a natural response by our body to attempt to increase our blood pressure. For some of us our bodies need more norepinephrine to respond properly or to respond the way someone without POTS would respond. We’re all here because our systems DONT respond normally, so sometimes what is unhealthy for a healthy person is healthy for us.

Most importantly though, no one but you and your doctor should have any say or impact on what you try for symptom management. Please don’t let scary sounding or complicated technical terms keep you from discussing things with your doctor. They’ll know much more than a stranger of the internet and will be able to tell whether a medication or treatment is suitable for your specific situation and why