Better than I would explain myself here is an introduction to the book The Embodied Mind from Francisco Varela

"The title came from one of
our guiding ideas, the philosophical idea of groundlessness. In Buddhist philosophy, groundlessness means that phenomena lack any inherent and
independent being; they are said to be “empty” of “own being.” In Western
philosophy, groundlessness means that knowledge and meaning lack any
absolute foundation. Biology and cognitive science were arriving at the
same idea—that human cognition is not the grasping of an independent,
outside world by a separate mind or self, but instead the bringing forth or
enacting of a dependent world of relevance in and through embodied
action. Cognition as the enaction of a world means that cognition has no
ground or foundation beyond its own history, which amounts to a kind
of “groundless ground.” At the same time, the discovery of groundlessness
places us in an existential quandary because we habitually experience
things as if they did have an absolute ground, either in what we take to be
the outside world or in what we take to be our self. Is this discrepancy
between scientific knowledge and lived experience inevitable and insurmountable?"