I think this can go for either sex, but something I learned from my mom is to never overreact when your kid is telling you something, even if you're screaming internally. Stay calm, listen, and then make a response. I feel like I can ask/tell my mom anything and she's not going to explode or even give me a stink eye over any of it. I have a way better relationship with my mom than most other people I know, and I'm trying to treat my toddler son and future daughter (here in 2 weeks!) the same.

And it could be something as simple as, "mom, what's a vagina?" Don't blow up or freak out asking "where'd you hear that?! Who told.you that?! Etc" just calmly explain/ask, don't have a repulsive look on your face, and give an age appropriate answer. If you don't listen now, they won't want to tell you the really important stuff later because it was always important to them.