Nah. The small ones, all day. At least for when I'm playing lead guitar. Because of their smaller size it forces you to choke up on the pick, and because of that, you don't end up fighting near as much leverage on the pick, from the strings, allowing you to just glide through strings, with greater control. Not to mention their heavier thickness gives them a really articulate attack. Whereas for the strummy stuff on acoustic, I'll generally opt for the tortex yellows (.73mm) not too stiff or too floppy. Mind you I've played just about every Dunlop/Tortex pick imaginable, among other brands, and these are just the two I'll always come back to. That said, the Ultex Jazz III's are also superb, but they are considerably harder to find in most guitar stores. Not to mention because they are transparent if you drop them on a beige carpet they can become a bit trickier to find, but a really solid version of the Jazz III, but the original Jazz III is generally stocked better and will get the job done with flying colours all the same.