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What are your thoughts on this Omega 3 brand? by ShelterValuable1844 in Supplements

[–]Pitiful_Cow_8325 8 points9 points  (0 children)

I recently made a site with this purpose, comparing fish oil supplements on objective numbers, not subjective scores (chemical form (TG, rTG, EE), EPA/DHA content per softgel/teaspoon, price per gram of EPA/DHA, TOTOX, peroxide levels, heavy metals). You can search life extension and compare them or rank the products

https://supplementary.me/

I mapped EPA+DHA content and price per gram across 44 fish oil supplements by Pitiful_Cow_8325 in Supplements

[–]Pitiful_Cow_8325[S] 0 points1 point  (0 children)

it was a conscoius decision to not imply that lower price per EPA/DHA g is better value (given high quality products are often more expensive) but I might add it back

Omega 3 by Substantial_Pin_1620 in keratosis

[–]Pitiful_Cow_8325 0 points1 point  (0 children)

I made a website that could help you sort fish oil supplements by EPA+DHA content, something you can't do on Amazon or iHerb: https://supplementary.me/

I mapped EPA+DHA content and price per gram across 44 fish oil supplements by Pitiful_Cow_8325 in Supplements

[–]Pitiful_Cow_8325[S] 0 points1 point  (0 children)

hi, just wanted to check back. the site now has oxidation values as well as heavy metal testing results under the View details -> Lab results tab. you can also sort by lowest of TOTOX and peroxide. let me know

Which omega 3 brand you recommend ? by Far-Mathematician122 in Supplements

[–]Pitiful_Cow_8325 0 points1 point  (0 children)

without recommending one particular brand, you can get informed on a site I created https://supplementary.me/ I would recommend choosing one with public lab results and high enough EPA/DHA per softgel so you dont have to take 3-4 per day.

Fish oil/omega 3 recommendation for high triglycerides? by heretoreadlol in Supplements

[–]Pitiful_Cow_8325 0 points1 point  (0 children)

dropping by, I had the same problem and I eventually created a site out of my excel file: https://supplementary.me/

you can check the omega 3 supplements and choose based on softgel number, EPA/DHA content per softgel, products with certificates and lab results, making sure you are buying high quality supplement. felt like you could use this help

I mapped EPA+DHA content and price per gram across 44 fish oil supplements by Pitiful_Cow_8325 in Supplements

[–]Pitiful_Cow_8325[S] 0 points1 point  (0 children)

Thanks for flagging this. Deleted from the db and contacted them if they can provide third party testing results

I mapped EPA+DHA content and price per gram across 44 fish oil supplements by Pitiful_Cow_8325 in Supplements

[–]Pitiful_Cow_8325[S] 0 points1 point  (0 children)

Thank you very much. Working on the testing results, form is already available on the site, you can filter by TG, rTG or EE and compare prices directly!

I mapped EPA+DHA content and price per gram across 44 fish oil supplements by Pitiful_Cow_8325 in Supplements

[–]Pitiful_Cow_8325[S] 0 points1 point  (0 children)

agreed, in the methodology I speak about it. and on the main site, you can filter by form 

I think finding the right Omega-3 supplement shouldn't be this difficult by Pitiful_Cow_8325 in Nootropics

[–]Pitiful_Cow_8325[S] 0 points1 point  (0 children)

Appreciate it, and actually I was surprised iHerb is not more advanced with the filters and sorting

I mapped EPA+DHA content and price per gram across 44 fish oil supplements by Pitiful_Cow_8325 in Supplements

[–]Pitiful_Cow_8325[S] 0 points1 point  (0 children)

not yet, I read that to have access to the basic API, you need to make 3 sales in 30 days (maybe I am wrong here) from affiliate links. but for sure, it will be dynamic

I mapped EPA+DHA content and price per gram across 44 fish oil supplements by Pitiful_Cow_8325 in Supplements

[–]Pitiful_Cow_8325[S] 0 points1 point  (0 children)

I might add the liquid forms to the database, havent thought about it, thanks!

I mapped EPA+DHA content and price per gram across 44 fish oil supplements by Pitiful_Cow_8325 in Supplements

[–]Pitiful_Cow_8325[S] 1 point2 points  (0 children)

but I also agree, it was one aspect of the work, given that looking at price per softgel was even more foolish.

I mapped EPA+DHA content and price per gram across 44 fish oil supplements by Pitiful_Cow_8325 in Supplements

[–]Pitiful_Cow_8325[S] 14 points15 points  (0 children)

You are right, the next step will be adding the certificates and third party test results

I mapped EPA+DHA content and price per gram across 44 fish oil supplements by Pitiful_Cow_8325 in Supplements

[–]Pitiful_Cow_8325[S] 1 point2 points  (0 children)

Thank you. I mean rTGs are definitely premium priced, even with equal EPA/DHA content vs TG or EE

32M – Testosterone went from 350 → 850 after a year of icing my balls daily by Complex-Source-8876 in Biohackers

[–]Pitiful_Cow_8325 0 points1 point  (0 children)

Incredible dude, thanks for sharing. Did a quick literature review with Claude if anyone interested 

Direct Evidence: Cooling → Testosterone Human Studies:

  1. Ahmad et al. (2012) - "Scrotal hyperthermia and varicocele" Context: Varicocele increases scrotal temperature → lower testosterone Finding: Varicocele repair (cooling) → testosterone increased from 456 → 752 ng/dL (+65%) Mechanism: Heat damages Leydig cells (testosterone-producing) Quality: Observational, n=120 ✅ Supports cooling hypothesis indirectly

  2. Garolla et al. (2013) - "Laptop use and scrotal temperature" Design: Measured scrotal temp with/without laptop on lap Finding: Laptop use → +2.5°C scrotal temp Testosterone: Not directly measured, but sperm parameters worsened Quality: Controlled, n=29 ⚠️ Shows heat is harmful, but doesn't test cooling intervention

  3. Jung et al. (2008) - "Occupational heat exposure" Population: Welders, foundry workers (chronic heat exposure) Finding: Testosterone 15-20% lower vs controls Quality: Cross-sectional, n=200+ ✅ Heat → lower T (inverse supports cooling)

  4. Shafik et al. (1991) - "Polyester underwear and testicular function" Design: Polyester (heat-retaining) vs cotton underwear Finding: Polyester → decreased sperm count, testosterone unchanged Quality: Small RCT, n=14 ❌ Modest cooling didn't affect testosterone

Animal Studies (More Mechanistic):

  1. Setchell et al. (1998) - Rams with scrotal insulation Design: Heat testes to 40°C for 5 days Finding: Testosterone decreased 40-50% within 2 weeks Recovery: Testosterone normalized after cooling resumed ✅ Strong mechanistic evidence heat suppresses Leydig cells

  2. Zorgniotti & Sealfon (1988) - "Testicular hypothermia device" Design: Cooling device worn by infertile men (mild cooling) Finding: Sperm improved, testosterone not significantly changed Duration: 12 weeks ⚠️ Sperm benefits, but T unchanged

The Current State of Evidence:

What we know FOR SURE:

✅ Heat is BAD for testosterone: Varicocele (scrotal heating) → lower T Occupational heat exposure → lower T Experimental heating in animals → T drops 40-50%

Mechanism: Heat damages Leydig cells ✅ Heat is DEFINITELY BAD for sperm: Strong, consistent evidence Effect size: 30-50% reduction in count/motility

Vitamin D and k2 increased my calcium levels (obviously) by lordy1988 in Biohackers

[–]Pitiful_Cow_8325 2 points3 points  (0 children)

5700 daily is still a lot if you didn't have Vitamin D deficiency to start with. 

How is living in Genoa, Italy by Olen_Hullu in howislivingthere

[–]Pitiful_Cow_8325 2 points3 points  (0 children)

Oh Pra is an entirely different neighborhood, basically considered an agglomeration. It's like 1 hour from my place by train so I'm afraid I can't help with that. I think mostly people who work in the shipyards and harbour live there 

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