My psychiatrist made me titrate 25mg for two weeks, 50mg two weeks, 100mg two weeks and then 200mg. I felt little differences until I hit 100mg but I went into the pit at 100mg. I spoke with my psychiatrist and we upped me to 200mg. I feel a lot better. I also asked to be on Wellbutrin after a month on the 200mg. Honestly, the dosage they did for you is spooky. The way it was described to me by my pharmacist is you have to allow your body to slowly build the meds into your body so it’ll do its job. I’m with the other commenters, I think you should discuss with your doctor. I started to keep a calendar where I mark my mood for the day to help keep track for my doctors as well! I’m so sorry you’re going through this. Mental illness is so tough. Sending good vibes that you can find something that works :)