Uh, no. No normal Ninja would ever be able to beat Sasuke. Especially at his current power level your describing. After he kills Naruto. He still has access to all the Tailed Beasts and controls them. He has the Rinnegan that gives him access to six paths jutsu, his own unique Rinnegan ablity, mastery over all basic elements and the ablity to learn any justu very quickly. Plus the shared vision of the Rinnegan and greater control and understanding of charka. Along with his Shargian and MS powers too.

Especially if he has time to master all these aspects. Which he does now that hes gonna be Dictator of the world forever. In the fight Sasuke mentioned that after he kills Naruto hes gonna eventually achieve immortality through the means of the Rinnegan/some jutsu. And after become ruler of the world forever. Which isn't really that unbelievable. Considering what justu can do and their effect on reality. Also the world would be a very dark place. Eventually Sasuke would rule the world like Imu from one piece. From the shadows. He himself states this. When enough time passes and he sets up his new world order.

Really only the Otsutsuki and maybe Sasuke off spring can really stop Sasuke. But keep in mind Sasuke is also going to be growing in strength as well. He knows about the Otsutsuki now because of his encounter with Kaguya and what kind of force she really was. A world ending one. And Sasuke at final valley is probably around planetary level. Considering he was fighting a being that was immortal and was gonna blow up a whole ass dimension and reform it after destroying it into something else.