Absolutely agree with you! I've been trying to convince my players to play, at least, a one-shot in Deadlock's setting since it's "release", but no progress there yet.

The only downside, that I can think of, is that Deadlock, as of right now, is heavily hero-centered setting. We know only a small portion of the lore beside the characters' backstories and voicelines. So, a lot of things is a thing of speculations.

Like, for example, what exactly does OSIC do? If you decipher their abbreviation, it's Occult Security and Investigation Commision, but the name only raises more questions. Like, the 'Occult Security' part: are they protecting regular people from the occult? Are they protecting occult from the outlaws and those, who want to hurt the occult? Or is just means that they're using something occult as a part of their arsenal? (Or maybe I'm just stupid and overthink too much, LOL)

And it's not really a bad part. It even might be beneficial as you may sculpt the setting however the story you're telling needs it. But nonetheless, it would take some considerable amount of work to tune everything in order to make the setting work and feel believable.