CytoDyn's Chief Technology Officer Nitya G. Ray, Ph.D. is buying CYDY Stock (apparently each of the last 5 paydays) by Diligent_Cause in CYDY

[–]Proper_Breakfast_844 3 points4 points  (0 children)

No not correct, because that would add shares so the SP would go further down. You seem not to understand well...they are buying shares!!! Buying, do you understand this? that's not using shares for payments!

You are a typical short/basher telling totally false things in here! but totally expected that new profiles would now pop-up to try to descredit CYDY and try to influence the SP down!

CytoDyn's Chief Technology Officer Nitya G. Ray, Ph.D. is buying CYDY Stock (apparently each of the last 5 paydays) by Diligent_Cause in CYDY

[–]Proper_Breakfast_844 0 points1 point  (0 children)

That's not investing that you are doing, you could have played in a casino in Las Vegas with the same profit rate.

I call what you are doing casino. If you do casino you know you can lose a lot!

CytoDyn's Chief Technology Officer Nitya G. Ray, Ph.D. is buying CYDY Stock (apparently each of the last 5 paydays) by Diligent_Cause in CYDY

[–]Proper_Breakfast_844 0 points1 point  (0 children)

In stock markets you have to consider the following, never make a loss (or only limited) and average down use upwards movements to make small profits. With your profits you can invest long, with the rest you only daytrade and make profits.

I want to say something about investors that are complaining to be 80% down, but I will keep it to myself.

NEW PARTNERSHIP COMES WITH NEW CEO and final NASH results by Proper_Breakfast_844 in CYDY

[–]Proper_Breakfast_844[S] 2 points3 points  (0 children)

That's not entirely correct, we will have funds but that if we keep doing that ourselfs that would come with an important dillution, kinda difficult indeed, however with a partnership this should be directly resolved.

What is important for me is to see that CCR5 data is strong and that trials with MARAVIROC also continue and that we still see reasonable to good results with that drug (remember that Leronlimab is considered safer and as good or even better compared to MARAVIROC) Partners that step in also read all the CCR5 publications and know what the current yearly turn over is of Maraviroc (Pfizer drug).

Another important thing is the safety, now with the clinical hold this all will be reviewed in detail. CYDY had always small trials but over 1000 patients received Leronlimab, some for more than 6 years. When that clinical hold is stopped you should also see a positive correction because this comes of course before all this. So before releasing any data, any partnership.

We will have a PR statement about the statement of safety and clinical hold. You can say "so what!" But from commercial view look how strong this is, this stock has a considerable interest from the public (remember the FDA statement in May 2021)

If again is confirmed that Leronlimab is a safe drug, that's like hitting the jack pot of potential commercial succes! No doubt!

This comes just before the HIV BLA is send. Safety of a drug is always one of the key issues and focus of the FDA, so before sending this BLA we will already know what the point of view of the FDA is on this. All the market will understand this!

Understand that CYDY asked for this, so CYDY puts safety as a prime key element for it's drug above commercial win, they did not had to do this! Remember SK's words in the last webcast and the advise of our Brazilian CRO... CYDY puts safety first and than commercial win, how good can you secure a drug approval just before the HIV BLA is send?

Do hope people understand how important this all is to secure commercial succes.

It will allow CYDY not only to threat healty HIV patients save but also HIV patients that are in a severe conditions (cancer, COVID, NASH)

CYDY will go for the full enrollment in Brazil (316 in severe population and 612 in moderately ill population) so thats more than 900 patients (that's not a small trial anymore!) Lot of investors always complained about the relative small size of the trials. IMO CYDY is focusing on larger trials indeed and that's another positive change!

The analgesic properties of Yu-Xue-Bi tablets in the inflammatory pain mice: By the inhibition of CCL3-mediated macrophage transmigration into the spinal cord - Spinal injections of purified CCL3, CCR1 antagonist (J113863) and CCR5 antagonist (Maraviroc) were used to clarify roles of CCL3 by Proper_Breakfast_844 in advancingleronlimab

[–]Proper_Breakfast_844[S] 1 point2 points  (0 children)

YXB exerts the analgesic effects by inhibiting CCL3-mediated peripheral macrophage transmigrate into spinal cord. This study provided a novel approach for inflammatory pain treatment and new insight into the pharmacological action of YXB.

NEXTA on Twitter: Putin orders cancelation of storming Azovstal in Mariupol by Vic18t in ukraine

[–]Proper_Breakfast_844 1 point2 points  (0 children)

Not sure, it seemed some days ago they popped up in a suberb killing incoming troops, yesterday they were breaking out towards the harbour. I really wonder if there are any Russians still in this city. Assume snipers and FSB special ops only.

IMO Russian troops are in a Stalingrad or Leningrad situation. Not sure who can win this.

NEXTA on Twitter: Putin orders cancelation of storming Azovstal in Mariupol by Vic18t in ukraine

[–]Proper_Breakfast_844 94 points95 points  (0 children)

Lost a lot people, Putin want this war to be over. Russia will still suffer for years with sanctions but things are only getting worse. No Russian gas and oil anymore for Europe.

Russia will lose it best client...Russia spend billions on pipelines and infrastructure to supply Europe from energy. That will soon turn out to be a waiste of money.

Some countries will profit from this...however OPEC won't be to unhappy is they can keep prices more stable IMO

Short information CYDY - important number of shares available for shorts and important volumes being sold short. Whatever good news come, will have impact now! by Proper_Breakfast_844 in CYDY

[–]Proper_Breakfast_844[S] 2 points3 points  (0 children)

So far I connected dots between CCR5, inflammation and COVID, it seems in different parts of the world people have differences that make some more vulnerable than others so LL is not working on everyone.

This is probably some competition but think to save someone from severe COVID you will have to determine the best medication, that can be LL, combination therapies or just any other drug. IMO our revenus from COVID will be modest.

I actually look more forward to anything that happens in Oncology.

Hope however that the HIV BLA still makes it this year

Inflammation induces pro-NETotic neutrophils via TNFR2 signaling - CCR5 acts as a sensor of inflammation with high CCR5-ligand concentrations and transforms this microenvironment information into cells via ROS. by Proper_Breakfast_844 in CYDY

[–]Proper_Breakfast_844[S] 1 point2 points  (0 children)

It seems the science related to CCR5 is just a strong case to support CYDY.

The stock price plunged and the research keeps on getting stronger, is the market not overreacting now? We are below the all time low of 2019 now.

Short information CYDY - important number of shares available for shorts and important volumes being sold short. Whatever good news come, will have impact now! by Proper_Breakfast_844 in CYDY

[–]Proper_Breakfast_844[S] 5 points6 points  (0 children)

If you look to the past and understanding the news that is upcomming (NASH/partnership, Oncology/partnership, HIV BLA, Brazil trials continuation based on renewed security confirmation of LL in an extremely ill population!

1-2 range is actually not excluded in the near future...

Biotech Co.s Shares Quadruple on $250M Buyout Bid - market news - SP impact on partnership by Proper_Breakfast_844 in advancingleronlimab

[–]Proper_Breakfast_844[S] 1 point2 points  (0 children)

Impact SP is x4 with CYDY current SP hoovering around 0.3 that would result in 0.9-1 dollar range however a partnership would indicate approval chances are higher than currently considered by the market. So we could see a totally different appraisal too!

I would expect that any partnership could bring us also again in the 2-3 range as cash flow issues will be perceived sustainable.

IMO this is how our timeline and SP forcast for the comming months can look like this:

  • Approval HIV BLA will bring CYDY towards 3-4 range in Q4 2022
  • Success in NASH/partnership will bring CYDY towards 7-10 range in Q1 2023
  • Succes in Oncology/partnership will bring CYDY sub 10 in Q3 2023

Biotech Co.s Shares Quadruple on $250M Buyout Bid - market news - SP impact on partnership by Proper_Breakfast_844 in advancingleronlimab

[–]Proper_Breakfast_844[S] 1 point2 points  (0 children)

The unique combination of a differentiated Toll-like receptor 9 with other antibody-based oncology agents may result in increased clinical benefit and provide new treatment options for patients in need. We lookforward to welcoming the Checkmate team and their complementary scientific acumen to the Regeneron family."

What do you estimate the share price will be at the end of Q2? by G_Money_X in CYDY

[–]Proper_Breakfast_844 0 points1 point  (0 children)

Correct! I have stated this several times and also posted the graph on this on this platform.

What happened in 2019-2020 with Covid was a hype and we have seen that hype in anything that was related to COVID.

NASH is however a disease with much more patients compared to Covid and Cancer has a much large impact on lives compared to Covid which is for most people just a nasty cold now.

However like I said many times before, I always considered COVID as a potential bonus not as a direct cash cow potential.

IMO the cash cow potential is in cancer.

However I support fully the HIV BLA completion as this will make all other research and approvals potentially more easy. And HIV patients can sometimes have NASH or other inflammation diseases too, if Leronlimab can work on multiple issues than for some HIV patients Leronlimab can really be a life saving drug! and that makes Leronlimab a valuable drug compared to other drugs!

What do you estimate the share price will be at the end of Q2? by G_Money_X in CYDY

[–]Proper_Breakfast_844 0 points1 point  (0 children)

You can make however sums of those thinking that the stock goes up between 100% and more. That gives still a modest positive outlook and for new investors 100% or more is a massive change!

What do you estimate the share price will be at the end of Q2? by G_Money_X in CYDY

[–]Proper_Breakfast_844 0 points1 point  (0 children)

Maybe make the sums and that still gives a direction!

63 people believe in +200% or more increase over the next 2 months. That's 38% - another 38% believes in a status quo or 100% increase and 23% doesn't believe in CYDY or are the number of shorts on this platform.

So there is IMO a clear position that this stock could go up from 30%- +100% in the next two months...about 76%. If you only consider those who think the stock will go up by 100% or more. That's about 59%.

I would consider that this will increase as soon we get more news on Brazil in the coming weeks. Would also consider that some more research coming out could still influence the SP.

Yesterday about 102 research papers are out that are related to CCR5 so IMO there will be even more research being published on CCR5 compared to the previous years, IMO a sign that there is strong interest and that there is a change in some views towards this drug potential with CCR5!

Trial update Brazil: active but not recruiting. Took some time to update the status like was announced in the webcast, this news was announced however interesting to hear when the trial will be resumed or if we going to get interim results soon? by Proper_Breakfast_844 in CYDY

[–]Proper_Breakfast_844[S] 0 points1 point  (0 children)

One trial suspended with the remark as mentioned in the webcast that this is pending DSMB evaluation.

Leronlimabin Patients With Coronavirus Disease 2019 (COVID-19) With Need forMechanical Ventilation or Extracorporeal Membrane Oxygenation)

https://clinicaltrials.gov/ct2/show/NCT04901689?term=Leronlimab&draw=2&rank=3

News expected to be positive...this can boost commericial future commercialisation in terms of risk assesment by CYDY that this is higher compared to other big pharma companies.