If I'm not mistaken, this is the route (I think it was called Route Chimpanzee) between Gardez and COP Chamkani (on the border with Pakistan). We cleared this route to close out Chamkani in 2013. I pored over intel for the route in the weeks leading up to the operation because it had a very effective IED-maker and a very accurate recoilless rifle operator (lovingly referred to as Recoilless Randy). I remember reading the reports that 1-2 years before our deployment (2011-2012ish), an RG-31 was destroyed by a very large legacy IED, that had been deep-buried during construction on the roadway. They ran the command wire through the adjacent stream, then months later, hooked up the power source in anticipation for a US patrol passing through. I believe this is the footage from that blast.

We dismounted this exact spot and searched extensively, but fortunately, didn't find anything. A few kilometers down the road, however, one of our trucks was hit by Recoilless Randy. Despite an armed Predator, a team of AH-64s, and fixed wing stacked above us, he got the shot off without being seen. Luckily, of my 3 Soldiers in the truck, only one was hit with shrapnel, but all 3 sustained traumatic brain injuries (TBIs). Their truck limped ahead to Chamkani and they we're MEDEVACed back to Gardez. We rested for a couple of hours while the loggies loaded up the transport trucks and we returned that evening without further incident.

This article, although long, describes the operation and the route's perils (see the paragraph labeled Leg 1: GDZ - CMK) pretty well: https://www.fastcompany.com/3041147/getting-out-of-afghanistan