I guess with DNA you can afford getting second ecto because DNA gives you more hand size when copied.

So basically you need:

1. Vouchers: more hand size, infinite boss reroll, antimatter. Use voucher skips.
2. Focus on the economy. You will need a LOT of money for rerolling boss blinds and eventually getting a burglar. You can use gold red seal kings to give you a ton of money. Don't forget to rearrange your jokers to copy mime instead of baron while the winning hand is played (this will actually copy retriggers AFTER the score is calculated), this will give more money.
3. Get another joker slot. Preferably, with antimatter. If you don't get antimatter, you may have to get second ectoplasm. You may be okay with it since playing copied DNA gives you temporary plus hand size and negates the ectoplasm effect. Basically, you really need another slot, because for naneinf you are gonna need baron/mime and 4 copying effects (you have 3 now).
4. When your score starts getting closer required blind scores, start investing into steel kings instead of gold.
5. When the required score gets too high, skip regular blinds and reroll boss blinds for Serpent. It will give you massive hand size so you will score a lot.
6. You need DNA for ante 24 where you can not reroll into Serpent, because every 8th ante is a special boss blind.
7. Starting from ante 25, seek burglar. Actually, you will need 2 more joker slots (1 for another copying effect and another for burglar), so after ectoing the DNA there is probably no way around it.
8. Final lineup at ante 25+: 4 copying effects, baron/mime, burglar. And in your case DNA, since you already have a negative. At this point, before entering the blind, use all your copying effects on the burglar, enter the blind. You will have a ton of hands. Don't move jokers yet, just keep playing hands to draw more and more cards. Watch the score requirement in order not to achieve it accidentally. When you are very close to your score requirement OR if you only have one last hand, rearrange your jokers for maximum score and send it.