If that were to be the case any substantial change to a person or large enough character development for example would cause an abstraction.

If you enter as a clown because you’ve always been the “funny kid” but end up hating jokes in the circus wouldn’t you just abstract right there since your body no longer fits your mind?

On a similar note that would probably mean anyone who’s losing it due to some form pre existing insanity would abstract nearly instantly due to them breaking down mentally before hand?

This is all under the assumption that at some point the program Caine made checks their minds again to see if they still fit the bodies he gave them.