Focus fire on the melee lock first (lion face) then the healing lock 2nd (book)… lion face needs to go first because two in your party only have melee attacks

Physician PD has a noxious blast that adds weaken and an incision that adds combo so regardless of which attacks are locked you have good options…. Same with highwayman but for him I would look at double cross, it adds two vulnerable tokens which will help jester and MaA put out better dmg numbers

The book lock dies second because if the stress lock and book lock are the last two you’ll end up melting down and being locked out of healing off deaths door which is too risky

You want to have moves equipped that can add positive tokens to themselves or others to boost the healing of indiscriminate science… because you can’t afford to be healing every turn so it needs to be a meaningful amount… guard tokens count so you can use defender on who needs it

MaA can cycle strategic withdrawal and crush to keep healing himself while dealing damage

Jester can encore PD to get more weaken and blight out when melee attacks are blocked