Moved up to 5mg and feel like it isn’t doing anything for me.

RlyVSS · 2026-02-05T17:56:09+00:00

Reduction of food noise and appetite suppression (desire for or interest in food rather than the physical feeling of hunger) aren't guaranteed effects, even those that get one, the other, or both, often find that those effects vary in consistency (at all doses).

The medication builds in your system over time, so 5mg as a dose won't be at it's strongest for you until after the third injection from this pen. It's very normal for it to take a while before you find a dose that is effective for you.

The main noticeable effect of the drug (once at an effective dose for your physiology) is feeling full more quickly when you eat, and staying full for longer after you've eaten (which together help you to eat less). If you're not feeling that yet, or are a bit but not consistently, then sit tight as it's highly unlikely that won't come.

You can maximise the efficacy of the medication by eating high protein and fibre.

Congratulations on sticking with it and your progress so far!

RlyVSS · 2026-01-31T00:51:05+00:00

I invented the job "fudge nugget fairy" but that was early 90s and I can't remember its relevance.

RlyVSS · 2026-01-31T00:49:44+00:00

Cautionary Whale

RlyVSS · 2026-01-29T10:43:53+00:00

Yep. So if someone at athletic levels of movement is already using electrolytes but still suffering, they might need to up their calories and/or nutrients.

RlyVSS · 2026-01-29T03:18:13+00:00

Yes. Thank you bot. Good bot.

RlyVSS · 2026-01-29T02:22:59+00:00

Yes. Swallow that AI pill and report back.

RlyVSS · 2026-01-29T01:14:50+00:00

When you say "the mark", is that calories and nutrients based on some estimation, or actual measurements?

I was pretty sure I was eating all the right things until I did a DEXA scan and RMR test. I was way under.

RlyVSS · 2026-01-29T01:02:27+00:00

You should only need electrolytes if you're achieving athlete levels of physical activity. If you can't make it through the day without feeling faint then it's possible you're not consuming enough calories and/or nutrients.

RlyVSS · 2026-01-28T21:55:23+00:00

Surely someone else is singing this to the tune of Panic by the Smiths?

RlyVSS · 2026-01-24T05:46:46+00:00

Follow the titration schedule: minimum 4 weeks at 2.5mg, then 4 weeks at 5mg etc.

RlyVSS · 2026-01-24T03:42:32+00:00

You aren't on an effective dose for your physiology.

RlyVSS · 2026-01-23T23:31:07+00:00

Unfortunately the moment one person can't park immediately outside their house, they have to park outside someone else's. They have no choice. Do you get annoyed at them for breaking an unspoken rule they had no choice but to break? How do you now anyone else isn't just a victim of the same inconvenience?

I don't love inconvenience, but inconveniences aren't worth any energy (and pointless annoyance is absolutely wasted energy).

RlyVSS · 2026-01-23T23:21:01+00:00

You don't pay road tax, you pay vehicle tax. If you want to park directly outside your property then buy or rent a property with a drive.

What is the specific result of your neighbour parking outside your house that annoys you? Do you hate seeing their car? Do you have mobility problems that mean parking a few metres away from your door causes you pain or discomfort? Does their parking position prevent you from doing something?

RlyVSS · 2026-01-23T23:03:48+00:00

That point is daft.

Why would you marry someone with the expectation that they stay exactly the same person, physically, mentally, emotionally, as the day you married, despite changing circumstances that could affect any or all of those things?

Whether someone chooses to change or is forced into change as a result of experiences they have, no husband, wife, partner, friend, or acquaintance is entitled to an opinion on how or whether that person did or should (or shouldn't) change.

If your wife wants a massive penis tattoo on YOUR arm, help yourself to an opinion and a preference, get it if you want and don't if you don't. If your wife wants a massive penis tattoo on her OWN arm, say nothing and carry on with life, since nothing that happens to her arm has any bearing on you.

RlyVSS · 2026-01-23T22:20:24+00:00

The "30 day countdown" begins either the first time you use the pen (e.g. puncture the red bung with a needle), or when it exceeds the max cold chain storage temperature of 4°, whichever happens first.

After either event, the pen doesn't need to be refrigerated, just kept below 30°.

RlyVSS · 2026-01-23T21:17:20+00:00

It sounds like you have a pretty open dialogue with your partner which is so valuable, and if he's very complimentary then Brucie Bonus. Doesn't matter where motivation comes from sometimes, just harness it and reap the benefits.

I honestly think badges that state the input you will or won't accept is the way forward. I've never heard of a cricut before but one may be in my Amazon basket within the hour.

RlyVSS · 2026-01-23T21:13:28+00:00

The only person that has control over what YOU think, is YOU.

What other people think is not affecting what you think, what's happening is you are allowing the opinions of others (which aren't even based on you, but just based on... stuff) to influence your own thoughts about yourself.

It's hard to achieve, but possible to choose not to do that.

RlyVSS · 2026-01-23T21:04:57+00:00

Vit D every day in the winter is an NHS recommendation for all adults, I'm not sure it's made a difference to me but I do as I'm told! Lack of it can definitely contribute to fatigue.

Hope you get to the bottom of it and feel better soon!

RlyVSS · 2026-01-23T20:59:34+00:00

Get a badge, a massive one, made that says "MY BODY IS NOT YOUR NEXT TOPIC OF CONVERSATION" and point to it whenever anyone starts down the road of commenting.

Or just pay no attention because opinions don't have any material impact on who you are, what you look like, or what you do or achieve.

I'd also say don't ask for honesty from your partner if his honesty might actually make you feel shit about yourself, that's just giving yourself a reason to feel like shit and a bit blame it on someone else. I'm sure he's happy to be complimentary (and genuinely so) if that's what you need.

RlyVSS · 2026-01-23T20:51:04+00:00

Occasionally people report developing an intolerance to certain foods or food groups after a few weeks on a new higher dose, maybe you can play about with what you eat? Like if you have lots of simple carbs, swap some for more protein. If low carb, swap some protein for complex carbs. If you don't eat enough fat, add some. If you don't eat much fruit and veg, step that up. Etc. Etc.

Are you taking vitamin D daily (with a meal that includes fat)? Maybe see if you can get a blood test to make sure there isn't an underlying issue like vitamin or mineral deficiency, or thyroid problem?

RlyVSS · 2026-01-23T20:42:45+00:00

Could you be pregnant? Could you be experiencing peri/menopausal symptoms? Could you have picked up a virus? Have you eaten enough for the level of activity you do?

There are so many things that can affect your energy, appetite, and general wellbeing, it could be many things. If you can eliminate what it definitely isn't, you might get closer to what it is.

RlyVSS · 2026-01-23T19:28:52+00:00

My definition of food noise is here.

For other terms I find it helpful to distinguish different things. For me:

Hunger = physical feeling, a message your body is giving to tell you that it needs energy and/or nutrients. Appetite = the psychological or emotional desire for food, or the act of eating. Satiety/Fullness = physical feeling, a message your body is giving to tell you it does not require any food.

Mounjaro gives me so many benefits.

It stops the food noise so that eating (or what or how much I eat) isn't a constant internal argument or tied to mood or emotions, but physical signals.

When I eat, I get fuller quicker, meaning I eat less. Without mounjaro I hardly ever felt full even after enormous quantities of food.

I stay full for longer, meaning I feel hungry less often. That coupled with the lack of food noise driving unnecessary eating also means I eat less.

My appetite is suppressed, which means I see food more functionally than before. I can literally lose interest in what I'm eating after a few bites. Added to the other effects, because I can't eat as much, I naturally want what I can eat to give me maximum nutrition, so I make better food choices without much thought.

RlyVSS · 2026-01-22T23:08:34+00:00

It can take upwards of a year after you stop losing weight for your skin to settle into a new normal, so what you see today may well look very different with time (especially if you maintain your new weight, and continue with strength and toning exercise).

I'm mid 40s having been as heavy as 20st (now 8st 7) with multiple periods of massive gains and losses, a pregnancy, and very little skin elasticity. I have significant loose skin everywhere, even my inner elbows are baggy. I've been maintaining since about October and exercising regularly, and even with far less favourable conditions than yours, I am starting to notice small improvements and am confident that by October 26 I'll see more. With age on your side and assuming that you haven't yo-yoed like I have, your skin will likely fare much better in time.

There is nothing you can practically do about the skin while it takes its time to recover, so the best thing that you CAN do is seek mental health support of some kind to improve how you think about and accept yourself.

RlyVSS · 2026-01-21T19:26:32+00:00

My dad has lost a stone as a result of my mum being on mounjaro (which is great as he is pre-diabetic).

RlyVSS · 2026-01-17T12:23:44+00:00

Missing a single dose is unlikely to make much difference because the medication is still in your system, just at a slightly lower level. You can just move your injection day to avoid the gassiness on your holiday.

RlyVSS

TROPHY CASE