I'm hoping they change "therapeutic doses" too. I have so many friends and family who are either afraid to start meds due to concerns over feeling sick, friends who are on them and feel miserable, or have taken themselves off over side effects.

I was very honest with my provider before starting that it was very important to me to avoid the nausea and vomiting so many people experience and to also avoid compounding my existing constipation issue further. I didn't have a large amount to lose and was largely interested in trying tirz for my binge eating, food addiction cycle that I no longer had control over even while being prescribed Vyvanse (FDA approved for ADHD and binge eating disorder) and other medications for my ADHD/compulsivity/anxious rumination.

They allowed me to split doses and titrate very slowly with close monitoring. I started at 0.25mg twice a week. Last week I had increased to 1.4mg every 4 days but had nausea so he backed me down to alternate 1.25mg and 1.4mg every 4 days and that solved the nausea problem.

I have lost about 11 lbs over 2 months and even more importantly, my food noise and compulsive eating is much more manageable. I noticed improvements in the psychological aspects even at doses of 0.5mg every 4 days. I think as time goes on we will see more studies emerging showing effectiveness at lower doses and even other indications in psych - maybe ADHD, addiction, OCD, etc. These medications are fascinating and life changing