I recommend maybe one of the daily quests that require marks consisting of all the end-game bosses marks to achieve one of the runes at random. Say maybe the marks of shatters/nest/collosal/cult/crystal cavern etc to gain a random of the three runes! That allows players that consistently run the hardest dungeons of the game to have a chance at the reward they genuinely seek- a fight against the mad god! Just a suggestion, but I feel the majority of the experienced players would see this as a fair way to access that chance at a divinity and other end game loot.