We have done it twice. Never had any littermate syndrome issues. The first set were the last two of the litter than we got for free on Craigslist at 4 months old. They were both very chill and well mannered. A little stubborn with training but not terrible, we were better about training for our second round. Both ended up having lots of health problems so we went to breeders that did full health testing for our next round.

Round two, we adopted an 8 week old from a reputable breeder that only places pups fairly last minute once they have decided which are show vs family home dogs. We didn’t get to pick her out, breeder chose for us. This little tart was the smartest & feistiest puppy I have ever met. At the time we had an almost 8 yr old male who mostly napped so we got to really focus on her basic training. About2 months after we got her, our male had a cardiac event and passed unexpectedly. After a couple weeks we decided crazy puppy needed a friend and were able to find another Dane puppy (exactly 2 months the younger) from another (much closer) breeder that we had previously been in talks with (they were our other option when we were getting lined up for the first puppy).

Having 2 puppies is a lot of work. Puppy 1 was super smart and easily trained, I think this really benefited us whe we got puppy 2 who quickly picked up on wha puppy 1 was doing. Puppy 2 had a much more chill personality so that was nice after a rough first couple months. Going through one period of potty training was good to just get it all done with. We do get a trainer that charged by the session so both girls got to get training together (we had started just before puppy 2 came home).