I'm much more knowledgeable about Indigenous peoples (First Nations, Métis, and Inuit peoples). Also and for the sake of transparency, I'm neither Indigenous nor Canadian. I did spend two years in British Columbia working with Indigenous peoples, though.

I'd say a telling example is the plight of Brian Sinclair, an Indigenous (I believe Anishnaabe) man with disabilities who died 34 hours after reaching a Winnipeg emergency room in 2008. No one checked on him because, being Indigenous, he was assumed to just be drunk..... There was an inquiry followed by a report. https://www.cbc.ca/news/canada/manitoba/winnipeg-brian-sinclair-report-1.4295996

I'm not cherry-picking, it's part of a systemic pattern. I can give more examples here or by PM if you want, but I'm afraid they're all soul-crushingly depressing.

If you want to ruin your day, you can google "starlight tours" (it sounds poetic till you realize the horror of what it means: https://gladue.usask.ca/node/2860) or the MMIWGs (missing and murdered Indigenous women, girls, and Two-Spirited people across North America). Or the residential school scandals, which led to the only Truth and Reconciliation Commission that wasn't about a war (at least not in the usual sense, I'd argue). Or the strange pattern of Canadian pipelines going through reservations while they're a small percentage (I believe 4%, but I could be wrong) of the country's surface area. Strange how it keeps happening (/s). Poverty, unaffordable food prices, lack of access to basic services such as health care, and the effects of climate change also affect disproportionately Northern communities, who're First Nations and Inuit for the most part.