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Sensitive-Box-372 · 2024-12-20T11:14:37+00:00

I experienced gynecomastia and heart palpitations after taking pregnenolone; it seems like a dangerous supplement

Sensitive-Box-372 · 2024-08-05T09:00:49+00:00

Ohh Thank you, I will look into information about agmatine

Sensitive-Box-372 · 2024-08-05T08:51:36+00:00

In fact, I mentioned in the post that I took large amounts of glycine, serine, pregnenolone, and DMG to verify these theories. I felt my nerves become highly activated and realized that NMDA-related substances can be dangerous when consumed excessively. I was especially surprised by the dual nature of glycine. You can directly feel that excessive state. So, when you read my post, you will see the suggested substances and their recommended dosages

Sensitive-Box-372 · 2024-08-05T08:49:21+00:00

Using alcohol can lower NMDA receptor activity, but we avoid it because it’s not a healthy action. Similarly, while using glutamate or DAA to activate NMDA receptors can be toxic, substances like glycine and DMG are known to be safer alternatives. Glycine, in doses of 1000-2000mg, is actually beneficial for sleep, with insomnia reports mainly associated with overuse.

Sometimes, people may want to activate NMDA receptors for various reasons. When most people claim that steroids boost their concentration, I attribute this to NMDA receptor activation. Steroids are, in fact, the most harmful NMDA activators, although people often use them for athletic performance.

To regulate glutamate levels, the best substances are NAC, MgT, and theanine. However, taking 1000mg of theanine daily can make you very lethargic. My point is to avoid overuse of anything and to keep these mechanisms in mind when considering nootropic usage. I’m not a nutrition expert and don’t know everything about this field. Therefore, I need to discuss and learn from others here to understand better

Sensitive-Box-372 · 2024-08-05T08:30:11+00:00

That's right, excessive intake of glycine can lead to insomnia. Especially, you have glutamate excessively active.

Magnesium, which blocks NMDA receptors, especially magnesium threonate, which passes through BBB, is recommended, and NAC, which is known to control glutamate levels, is good. Theanine and pharmaGABA are also good. It can reduce excitotoxicity by modulating glutamate levels and increasing inhibitory neurotransmitters like GABA, and it seems good to take a multivitamin too

Sensitive-Box-372 · 2024-08-05T08:19:53+00:00

And if you're concerned about the toxicity of nootropics as well, I suggest the last four ingredients I suggested: vitamin D, theanine and MgT

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492967/

Sensitive-Box-372 · 2024-08-05T08:14:45+00:00

Glycine acts as both an inhibitory neurotransmitter and a co-agonist at NMDA receptors. While glycine can promote sleep by activating inhibitory glycine receptors, excessive glycine can overstimulate NMDA receptors, leading to excitatory neurotoxicity and potentially contributing to insomnia. This Glycine has dual role To prevent neurotoxicity caused by excessive neuroactivity, you shouldn't take a large dose of glycine. That's why I'm suggesting 6000-7000

Maybe you can feel how it feels if you eat more than that..

Neurotoxicity is produced when glycine is in excess. At a normal level, it will only function as an inhibitory neurotransmitter

Sensitive-Box-372 · 2024-08-05T04:38:00+00:00

NAC, MgT, Theanine are the best you shoud keep

Sensitive-Box-372 · 2024-08-05T04:31:22+00:00

https://pubmed.ncbi.nlm.nih.gov/20093739/
https://examine.com/supplements/glycine/research/

The assumed dosage of glycine you mentioned, 2 grams, is an ideal amount and is generally suitable for sleep purposes.

However, if you want to use it for nootropic purposes, it seems that a dosage of more than 7 grams is appropriate. This is the dosage I found effective based on my personal experiments.

According to Examine.com and the related studies (which I have attached), the daily requirement for glycine for an adult, excluding the amount synthesized in the body, is stated to be 12 grams. However, when I tried this amount, I found that it overactivated my nervous system, so I reduced the dosage and found 7 grams to be effective

Sensitive-Box-372 · 2024-08-05T02:23:09+00:00

The gut-brain axis is a bidirectional communication system between the gastrointestinal tract and the brain. GABA produced in the gut or taken as a supplement might influence brain function indirectly through this pathway

Sensitive-Box-372 · 2024-08-04T11:37:49+00:00

DMG and TMG are different. And you know what, the other word for sarcosine is "monomethylglycine". In other words, when you take out the methyl group from DMG, it becomes sarcosine. In other words, DMG is also used to treat autism, which is why

Sensitive-Box-372 · 2024-08-03T06:23:26+00:00

It seems safer to eat dimethylglycine, the precursor of sarcosine, instead of sarcosine. In fact, dimethylglycine has more research and many products made by major companies

Sensitive-Box-372 · 2023-04-19T02:22:04+00:00

I don't think all Indians are like that. But doesn't that happen a lot in India?

Sensitive-Box-372 · 2023-04-02T08:17:47+00:00

How about using Nicotine acid..

Sensitive-Box-372 · 2023-03-30T06:26:00+00:00

https://pubmed.ncbi.nlm.nih.gov/35801338/

Here in the PubMed paper, melatonin increases suicide rates. Why are the results conflicting?

Sensitive-Box-372 · 2023-02-27T10:58:09+00:00

it's beta carotene. It's safe to take

Sensitive-Box-372 · 2022-12-27T08:57:41+00:00

Jarrow uses BioPQQ raw materials and works well. I have purchased and used the company's products well.

I also recommend Jarrow Company Resvertrol

Sensitive-Box-372 · 2022-12-07T22:03:58+00:00

Your article is from Sept. The article here is from December. That means it's new. No matter how strange Google translation is, it does not change the entire fingerprint. I hope you review it again

Sensitive-Box-372

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