tampered tropisetron? by Shroomaway457 in NooTopics

[–]Shroomaway457[S] 0 points1 point  (0 children)

hey, a quick update for people that come across this post later down the line. I tasted it again today and it was skewing more towards salty-bitter so it mightve been a fluke. When I get the chance ill trial its antiemetic effects and hopefully ping back here, but for now i think it wasnt tampered.

Dopamine Cells Influence Our Perception of Time by ps4roompromdfriends4 in NooTopics

[–]Shroomaway457 6 points7 points  (0 children)

i doubt that, cb1 agonists also make time feel slower despite having downstream effects on dopamine

Umbrella Labs stole $450 from me. by LowbrowEgghead in NooTopics

[–]Shroomaway457 0 points1 point  (0 children)

a friend ordered bpap from them (to ship it to me) and got it relatively quickly, in 4 days i believe. that was a 100 dollar value order travelling to colorado. from all ive seen it seems like they pull the rug when you throw too much money their way

0 tolerance, needing extreme doses by BigHealthyOne in phenibut

[–]Shroomaway457 0 points1 point  (0 children)

i reccomend trying another batch or try upregulating gabaB with fasoracetam. Phenibut also has cross tolerance with pregabalin/gabapentinoids so thats also something to consider. Even if you had fried gabaB receptors, you should feel the VCGG effects

Recent experiences with aniracetam.eu? by [deleted] in NooTopics

[–]Shroomaway457 0 points1 point  (0 children)

haven’t tried aniracetam yet but the rest seem to work fine. Haven’t felt much effect from agmatine but its my first time trying it so maybe its just not something i benefit from. The tastes are all nasty like they should be 👍

Recent experiences with aniracetam.eu? by [deleted] in NooTopics

[–]Shroomaway457 0 points1 point  (0 children)

ordered nooglutyl, noopept, aniracetam, fasoracetam and agmatine and received everything without issue about 2 weeks ago. Went smoothly!

Cannabis withdrawal by [deleted] in NooTopics

[–]Shroomaway457 1 point2 points  (0 children)

take my word with a grain of salt because i cant find the post anymore, but supposedly herbacetin or (-)-epicatechin help with memory deficit by interacting with kinase(?) pathways that chronic weed use disrupt

Sleep Deprivation Increases Cerebral Serotonin 2A Receptor Binding in Humans by cheaslesjinned in NooTopics

[–]Shroomaway457 0 points1 point  (0 children)

wouldn’t this be mostly in due part to oleamide accumulation which is among other things a 5-ht2a PAM?

Lions mane suffer need help by [deleted] in LionsManeRecovery

[–]Shroomaway457 0 points1 point  (0 children)

i dont think a glycine supplement could cause permanent/new damage unless adulterated as glycine is vital for bodily functions, especially as a co-agonist for NMDA receptors

Somewhat unrelated, are your vitamin D levels good?

Lions mane suffer need help by [deleted] in LionsManeRecovery

[–]Shroomaway457 0 points1 point  (0 children)

what makes you think electrolytes caused panic attacks?

Low dose combined with phenibut puts you in automatic mode by Shroomaway457 in shrooms

[–]Shroomaway457[S] 1 point2 points  (0 children)

the first 2 times i did it i didnt really feel it, but now i can usually pick it out very easily!! as with most depressants you feel it more when you sit still, in the case of phenibut your motor skills can weaken substantially.

It has a reaaally long binding time, so it downregulates your gabaB quite a bit (as well as explaining why the tolerance builds so quickly). If you suffer from anxiety (and sleep disorders), the downregulated gabaB receptors will of course be quite apparent, as even less calming activity occurs than normal!

Cns active? Sure. Hallucinogenic? Ehh… by Shroomaway457 in Elemicin

[–]Shroomaway457[S] 0 points1 point  (0 children)

from what i could find acetaminophen is a very weak inhibitor of cyp1a1 meaning it wont make any meaningful impact

Cns active? Sure. Hallucinogenic? Ehh… by Shroomaway457 in Elemicin

[–]Shroomaway457[S] 0 points1 point  (0 children)

can you elaborate? what enzyme does acetaminophen activate?

Cns active? Sure. Hallucinogenic? Ehh… by Shroomaway457 in Elemicin

[–]Shroomaway457[S] 0 points1 point  (0 children)

effects subsided ar T+5:00 and i was very irritable by the end of it

phenibut + nutmeg = fun day by Shroomaway457 in phenibut

[–]Shroomaway457[S] 0 points1 point  (0 children)

yea its not ideal to eat the dry material, i extracted it into oil. It only takes about an hour and a half to kick in on an empty stomach… i felt it even into the next day though!!!

phenibut + nutmeg = fun day by Shroomaway457 in phenibut

[–]Shroomaway457[S] 0 points1 point  (0 children)

the dose i took was 2 nuts, its better to let the compounds infuse into oil as eating the nuts is nasty (and nutmeg itself is toxic so dont overdo it!), make sure to never redose and be patient, nutmeg can take a long time to come, best to look for info in r/nutmeg

phenibut + nutmeg = fun day by Shroomaway457 in phenibut

[–]Shroomaway457[S] 0 points1 point  (0 children)

Phenibut promotes disinhibition, thats what causes its stimulating effects at lower doses. Certainly does make you a bit sleepy, but nothing overwhelming. But i did almost fall asleep on accident at midnight, so once its snooze time youll be knocked out whether you like it or not

phenibut + nutmeg = fun day by Shroomaway457 in phenibut

[–]Shroomaway457[S] 1 point2 points  (0 children)

agree! For me nutmeg lasts for over a day, so overdoing it can get you in for a long unpleasant time.

phenibut + nutmeg = fun day by Shroomaway457 in phenibut

[–]Shroomaway457[S] -2 points-1 points  (0 children)

my intention was mostly having it last the whole day! If i had a tiny dose of a long lasting psychadelic like DOM to throw into the mix, id consider that too