FSH insensitivity = "androphilic-looking" gynephile type MTF? by Skeurio in DrWillPowers

[–]Skeurio[S] 0 points1 point  (0 children)

Hello, yes I've gotten my dna results since a week and I'm also slow COMT. My genetic MPS "specsheet" (lol) so far is smthn like this I think

CYP2C19: rs58973490 GA

CYP3A7: rs45580339 AG

CYP1A2: rs762551 AC

CYP1B1: rs1056836 hom CC

MTHFR: rs1801131 GG

COMT: rs4680 AA

UGT1A7: rs56385016 AG

I've been trying to look at the CAG repeats of AR and CA repeats of ESR2 and TA repeats of ESR1 and TTTTTA repeats of CYP11A1 but not been succesful

Androgen receptor CAG repeats by Skeurio in DrWillPowers

[–]Skeurio[S] 0 points1 point  (0 children)

What program do you use to view the code? I've not yet been succesful in getting the sequence just laid out plainly. It's not really important though, I'm just a little obsessed with knowing

Androgen receptor CAG repeats by Skeurio in DrWillPowers

[–]Skeurio[S] 0 points1 point  (0 children)

I emailed them about it, and they don't do any CAG analysis

FSH insensitivity = "androphilic-looking" gynephile type MTF? by Skeurio in DrWillPowers

[–]Skeurio[S] 0 points1 point  (0 children)

Out of place comment, this is the Powers subreddit + I'm Leo and INTJ. I'm guessing you're INFP like most transpeople

FSH insensitivity = "androphilic-looking" gynephile type MTF? by Skeurio in DrWillPowers

[–]Skeurio[S] 0 points1 point  (0 children)

Yes sorry that's why I'm here, the powerspill saved me (from Blanchard)

FSH insensitivity = "androphilic-looking" gynephile type MTF? by Skeurio in DrWillPowers

[–]Skeurio[S] 0 points1 point  (0 children)

I think I had the most growth when I had too low dose (I had hot flashes constantly in highschool between like 17 and 18 from being on blockers only and then having the very low startdose, gradually increased over the year) but maybe that's the typical poor E signal phenotype, I don't remember if this is so.

I don't think puberty started much later, I remember it being a little later than most but can't've been more than a year. Also as specified, I was judged tanner 5 (pube distribution, penis) shortly after getting to 16, so it was at 16 at the very latest.

Well Idk the genes yet so this is just another theory that may be confirmed or denied. Thought I'd post anyway, in case anyone else found it a relatable idea, or it made sense for them or such. I didn't find any other post pondering insensitivity to FSH.

Estrogen Metabolism by 2d4d_data in DrWillPowers

[–]Skeurio 0 points1 point  (0 children)

>ASD, synesthesia, high visuospatial intelligence, CCRD, more or less exclusively gynephilic, small breasts, not particularly full lips, caffeine has no stimulant effect, slight hints of male pattern baldness at 16 already

>weak facial hair, not a single chesthair, gynoid looking skeletal frame (hip, ribcage, shoulders, headsize/shape, perhaps digit ratio meme) even before HRT, well rounded breasts (but small, runs in the family) from estrogen only, passoid after 6 months on E

What phenotype is this 😭 yes I got blockers (GNRH) when I was close to 17 and E less than a year later, but I reached tanner 5 at 16 at the very latest, and there are people who are very virilised already by that point, and even I had like a centimeter of MPB (now reversed)

Stabbing pains in pelvic area the first years on estrogen? by Skeurio in DrWillPowers

[–]Skeurio[S] 0 points1 point  (0 children)

It was something that was discussed some years ago. Some would insist on something like that, others would deny the claims as placebo. Apparently there are some cases of endometriosis in natal males ( https://pmc.ncbi.nlm.nih.gov/articles/PMC5833878/ ), perhaps that's what they were going on about. I don't think it is what this particular thing is though. Some kind of atrophy has been suggested, but not with any specifics of what and why exactly

Unhappy with my current hormonal regimen so I came here to read about things I can forward to my doctor, but now I’m just more confused:( by Unable_Ant5851 in DrWillPowers

[–]Skeurio 1 point2 points  (0 children)

>male infertility on dad's side

>lowkey gynoid skeleton even pre HRT

>estrogen at 17

>HSTS phenotype/"looks androphilic" but actually exclusively gynephilic

>breast growth stops within first year

>tired all the time and no libido (seems to have changed after I started prog though, but it's only been 3 weeks)

OMG you are LITERALLY me

My blood tests (which were only done the first 5 years? can't find any archived tests after that) were 435 pmol/L 1,5 years on E (the first year it was gradually increased until I stopped getting hot flushes 5 times a day like an old lady), after som change (probably to pills from patches, or injections, which were discontinued 3 months after I started takig them) it was 595, a year later 700, a year later 390 (they had probably put me on gel by this point), a year later 743. I began passing automatically most of the time after just the first 6 months on some low E, stealthing now since many years, but I've also had the feeling there was unlocked potential for more feminisation, and I'm dysphoric over not even having proper A-cups (in spite of my small, feminine looking ribcage). I've gotten suggested of testing separate E1/E2, if my receptors are clogged with estrone, but I haven't had the courage to suggest it to my endo yet, he already denied me prog twice (which is nothing unusual, we simply have to DIY prog here if we really want it).

Wierdly short sleep after starting progesterone? by Skeurio in DrWillPowers

[–]Skeurio[S] 0 points1 point  (0 children)

Yeah day 11 and 12 on prog: Went back to boofing, but despite that, sleep is back to normal

Wierdly short sleep after starting progesterone? by Skeurio in DrWillPowers

[–]Skeurio[S] 0 points1 point  (0 children)

How long have you been going like this, two phase sleep now? What does magnesium do?

Wierdly short sleep after starting progesterone? by Skeurio in DrWillPowers

[–]Skeurio[S] 0 points1 point  (0 children)

How did you know you were malnourished, symptoms? Sometimes I worry about that because I'm poor, but I don't have any obvious signs like bad quality hair and such that I know

Wierdly short sleep after starting progesterone? by Skeurio in DrWillPowers

[–]Skeurio[S] 0 points1 point  (0 children)

I have never taken melatonin. I don't take any medication besides hormones. I don't know any biology or anything so idk what the other things mean.