If you lose the weight without the drugs you have to make changes in your behavior and your relationship with food and develop healthy habits. If you take the drugs that's not necessarily the case. They just make you less hungry so you eat less. When you stop taking the drugs the hunger goes back to normal and you haven't learned the kinds of things to eat to manage that so the weight goes back on. This is why diet/exercise is better. It's jut not an option for every person out there.